{
  "abstract": "Three-dimensional (3D) printing of eco-friendly, naturally derived biopolymers such as chitosan offers great potential for biomedical applications. In this work, Eurycantha calcarata insects were used as the source of chitosan with a yield of 22.2% and a deacetylation degree of 77-78%, comparable to that of commercial chitosan. After extraction, characterizations were performed on the obtained compound (including FTIR, NMR, SEM, TGA, and XRD). Formulated into chitosan:gelatin hydrogels (EC:G = 1:3, 1:4, 1:5), the blends exhibited solid-liquid transitions at 29-33 °C depending on gelatin content. 3D-printed scaffolds achieved >90% shape accuracy and remained stable for 21 days in a culture medium. HeLa cells cultured on the scaffolds showed up to 99.6% viability after 3 days, demonstrating excellent cytocompatibility. By valorizing insect-derived waste, this work presents a sustainable and high-performance chitosan bioink, addressing the growing demand for eco-friendly materials in 3D bioprinting.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "name": "Zhenying Mei"
    },
    {
      "name": "Julie Lagouarde"
    },
    {
      "name": "Olga Volkova"
    },
    {
      "name": "Virginie Baylot"
    },
    {
      "name": "Christophe Candet"
    },
    {
      "name": "Philippe Barthélémy"
    },
    {
      "name": "Pavel Kuzhir"
    },
    {
      "name": "Guilhem Godeau"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/44dqtc3ts9xps.bib",
  "cited_by": 0,
  "doi": "10.1021/acsomega.5c10302",
  "fulltext_url": null,
  "id": "44dqtc3ts9xps",
  "issns": [
    "2470-1343"
  ],
  "landing_url": "https://hal.science/hal-05765476v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "hal",
      "1.chim.mate"
    ],
    [
      "openalex",
      "2204|3D Printing in Biomedical Research"
    ]
  ],
  "openalex": "W7161798816",
  "pdf_url": "https://hal.science/hal-05765476/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-26",
  "publisher": "ACS Publications",
  "ris": "https://research.draconitic.com/paper/44dqtc3ts9xps.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:41Z",
      "native_id": "hal-05765476",
      "source": "hal",
      "url": "https://hal.science/hal-05765476v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "hal:1.chim.mate",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Novel Chitosan Bioink Derived from Eurycantha calcarata (Lucas, 1869) for 3D Bioprinting of Cell-Compatible Scaffolds",
  "title_text": "Novel Chitosan Bioink Derived from Eurycantha calcarata (Lucas, 1869) for 3D Bioprinting of Cell-Compatible Scaffolds",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:41Z",
  "url": "https://research.draconitic.com/paper/44dqtc3ts9xps",
  "venue": "ACS Omega",
  "versions": []
}