{
  "abstract": "Acetylene is among the cheapest and most abundant C2 feedstocks, yet catalytic methods that exploit both of its π-bonds remain scarce, and its use in fine-chemical synthesis is 15 confined largely to mono-functionalization. Here we report the traceless bridging of aldehydes and formamides with a single acetylene molecule through a catalytic double hydroacylation, in which direct hydrogen-atom transfer generates acyl and carbamoyl radicals without decarbonylation or any sacrificial group. Coupling of two identical radicals assembles 1,4-diketones and 1,4-diamides in a single operation, whereas the sequential 20 delivery of two different radicals provides unsymmetrical 1,4-dicarbonyl products with good cross-selectivity. The transformation accommodates aromatic and aliphatic aldehydes and diverse formamides, proceeds under mild conditions with 100% atom economy, and requires",
  "abstract_shown": true,
  "affiliations": [
    "Engineering",
    "Zhejiang Sci-Tech University",
    "Zhejiang Provincial Innovation Center of Advanced Textile Technology",
    "Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering",
    "South China University of Technology"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Jialin Li"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Siwen Wang"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Yaozu Zhu"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Dong Zhu"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Yiping Fan"
    },
    {
      "affs": [
        0,
        1,
        2,
        3,
        4
      ],
      "name": "Shifa Zhu",
      "orcid": "0000-0001-5172-7152"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4739h0a345sje.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010342/v1",
  "fulltext_url": null,
  "id": "4739h0a345sje",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010342/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Radical Photochemical Reactions"
    ]
  ],
  "openalex": "W7221689605",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010342/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-13",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/4739h0a345sje.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:24Z",
      "native_id": "10.26434/chemrxiv.15010342",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010342/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Radical Photochemical Reactions",
      "subfield": "organic"
    }
  ],
  "title": "Acetylene as a C2 bridge for modular 1,4-dicarbonyl synthesis",
  "title_text": "Acetylene as a C2 bridge for modular 1,4-dicarbonyl synthesis",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:24Z",
  "url": "https://research.draconitic.com/paper/4739h0a345sje",
  "venue": "ChemRxiv",
  "versions": []
}