{
  "abstract": "This work focuses on the development of a new methodology for the regioselective functionalization of 4-azaindazole and 7-azaindazole N -oxide through oxidative alkenylation, specifically targeting the pyridine moiety. The study explores an unexplored area of regioselective oxidative alkenylation of 6,5-fused bicyclic compounds within the six-membered ring. The research also reports the isolation and characterization of hydroxylated products, involving C-O bond formation, which emerged as significant side products during this investigation. In this approach, N -oxide is proposed to play a dual role as a traceless directing group as well as a source of an oxygen atom. This catalytic method involves the simultaneous formation of new C−C and C−O bonds.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "name": "Hassan Harrouni"
    },
    {
      "name": "Sarah Nassiri"
    },
    {
      "name": "Marie-Aude Hiebel"
    },
    {
      "name": "Franck Suzenet"
    },
    {
      "name": "Gérald Guillaumet"
    },
    {
      "name": "Saïd El Kazzouli"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4agfxqj8a8b6z.bib",
  "cited_by": 0,
  "doi": "10.1016/j.tchem.2026.100167",
  "fulltext_url": null,
  "id": "4agfxqj8a8b6z",
  "issns": [
    "2666-951X"
  ],
  "landing_url": "https://cnrs.hal.science/hal-05775153v1",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "openalex",
      "1605|Catalytic C–H Functionalization Methods"
    ]
  ],
  "openalex": "W7171765423",
  "pdf_url": "https://www.tetrahedron-chem.com/article/S2666-951X(26)00015-X/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-02",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/4agfxqj8a8b6z.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:46Z",
      "native_id": "hal-05775153",
      "source": "hal",
      "url": "https://cnrs.hal.science/hal-05775153v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Catalytic C–H Functionalization Methods",
      "subfield": "organic"
    }
  ],
  "title": "Regioselective oxidative alkenylation of 4-azaindazole and 7-azaindazole N-oxides at the six-membered ring: N-oxide-mediated hydroxylation",
  "title_text": "Regioselective oxidative alkenylation of 4-azaindazole and 7-azaindazole N-oxides at the six-membered ring: N-oxide-mediated hydroxylation",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:46Z",
  "url": "https://research.draconitic.com/paper/4agfxqj8a8b6z",
  "venue": "Tetrahedron Chem",
  "versions": []
}