{
  "abstract": "This study presents a UAE-LC-MS/MS method for the extraction and quantitation of 6PPD-Q in stormwater sediment matrices. The final method uses ultrasonic-assisted extraction with a hexane:ethyl acetate solvent system and LC-MS/MS instrumental analysis with matrix-matched calibration, and demonstrated acceptable sensitivity, selectivity, and reproducibility. This study addressed challenges specific to sediment matrix, a lack of commercially available reference material, and co-extracted chromatographic interferences. Matrix effects were reduced through optimized extraction parameters, rather than post-extraction cleanup procedures. A total of 28 sediment samples were analyzed using LC-MS/MS to evaluate 6PPD-Q concentrations, resulting in values ranging from 11.4 ng/g to 691 ng/g, with a mean value of 171 ng/g. The method achieved a method detection limit of 1.1 ng/g and limit of quantitation of 5 ng/g using a 250 mg sample size. The mean recovery rate of 6PPD-Q in laboratory control samples was 80.1% (range: 74.8% - 82.3%).•Extract sediment sample with hexane:ethyl acetate mix and dry.•Reconstitute with acetonitrile.•Analyze using LC-MS/MS.",
  "abstract_shown": true,
  "affiliations": [
    "City of Tacoma Environmental Services Laboratory, 326 E D St., Tacoma, WA, 98421, United States."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Thomas Chontofalsky"
    },
    {
      "affs": [
        0
      ],
      "name": "Fatima Alsinai"
    },
    {
      "affs": [
        0
      ],
      "name": "Terri Torres"
    },
    {
      "affs": [
        0
      ],
      "name": "Monica Herbert"
    },
    {
      "affs": [
        0
      ],
      "name": "Tiffany Ryan"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4b90v0he23h71.bib",
  "cited_by": 0,
  "doi": "10.1016/j.mex.2026.104178",
  "fulltext_url": "https://europepmc.org/articles/PMC13677957",
  "id": "4b90v0he23h71",
  "issns": [
    "2215-0161"
  ],
  "landing_url": "https://europepmc.org/article/MED/42898596",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1602|Analytical chemistry methods development"
    ]
  ],
  "openalex": "W7214710825",
  "pdf_url": "https://europepmc.org/articles/PMC13677957?pdf=render",
  "pmcid": "PMC13677957",
  "pmid": "42898596",
  "published": "2026-09-29",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4b90v0he23h71.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:37Z",
      "native_id": "MED:42898596",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42898596"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1602|Analytical chemistry methods development",
      "subfield": "analytical"
    }
  ],
  "title": "Novel method for extraction and quantitation of 6PPD-Q in solid matrices using ultrasonic-assisted extraction (UAE) and liquid chromatography-tandem mass spectrometry (LC-MS/MS).",
  "title_text": "Novel method for extraction and quantitation of 6PPD-Q in solid matrices using ultrasonic-assisted extraction (UAE) and liquid chromatography-tandem mass spectrometry (LC-MS/MS).",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:37Z",
  "url": "https://research.draconitic.com/paper/4b90v0he23h71",
  "venue": "MethodsX",
  "versions": []
}