{ "abstract": "Obesity is a multifactorial condition posing an escalating public health burden in South Africa, where access to effective, evidence-based interventions remains constrained. This overview describes the South African adaptation of the Canadian Adult Obesity Clinical Practice Guideline, contextualized through locoregional evidence to provide pragmatic, setting-appropriate recommendations and culminating in a comprehensive 18-chapter guideline. Key areas of uncertainty — including HIV-associated weight trajectories and culturally specific perspectives on obesity — are acknowledged, with guidance offered where evidence permits. This guideline addresses a critical gap in culturally responsive, resource-sensitive obesity management within the African healthcare context.", "abstract_shown": true, "affiliations": [ "Division of Endocrinology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa", "Cape Town Bariatric Clinic, Kingsbury Hospital, Cape Town, South Africa", "Department of Psychiatry, Stellenbosch University and Department of Psychology Tygerberg Academic Hospital, Cape Town, South Africa", "Mental health, Alcohol, Substance use and Tobacco Research Unit, South African Medical Research Council; Department of Psychiatry and Mental Health, University of Cape Town; Institute for Life Course Health Research, Department of Global Health, Stellenbosch University, Cape Town, South Africa", "Division of Endocrinology, Department of Internal Medicine, Helen Joseph Tertiary Hospital and University of the Witwatersrand, Johannesburg, South Africa", "M-Care Optima Bloemcare Psychiatric Hospital, Bloemfontein, South Africa", "Center for Advance Medicine, Johannesburg; Chris Hani Baragwanath Academic Hospital, University of Witwatersrand, Johannesburg, South Africa", "Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa", "Burden of Disease Research Unit, South African Medical Research Council; Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Cape Town, South Africa", "Atrium Diabetes Center, Gillits, Kwazulu-Natal; Dept of Family Medicine University of Pretoria, Pretoria, South Africa", "Division of Endocrinology, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital and University of the Witwatersrand, Johannesburg, South Africa", "Biomedical Research and Innovation Platform, South African Medical Research Council, Cape Town, South Africa", "Life Kingsbury Hospital, Cape Town, South Africa", "Department of Surgery, Sefako Makgatho Health Science University and Dr George Mukhari Academic Hospital, Ga-Rankuwa, Pretoria, South Africa", "Department of Psychiatry, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa", "Physical Activity, Sport and Recreation (PhASRec), Faculty of Health Sciences, North-West University, Potchefstroom, South Africa", "Sunward Park Medical Center, Boksburg, South Africa", "Zuid Afrikaans Hospital, Pretoria, South Africa", "Zuid-Afrikaans Hospital; Dept Internal Medicine University of Pretoria, Pretoria, South Africa", "Obesity Canada, Edmonton, AB, Canada", "Busamed Gateway Private Hospital, Umhlanga, Durban, South Africa", "Zuid Afrikaans Hospital, Obesity Health Centre; Department of Surgery, Sefako Makgatho Health Sciences University, Pretoria, South Africa", "Department of Psychiatry, University of Toronto, Centre for Addiction and Mental Health, Toronto, ON, Canada", "Bariatric Surgery Program, University Health Network, Toronto, ON, Canada", "Private Practice and CPR Trial Centre; Mediclinic Private Hospital, Worcester, South Africa", "Division Surgery, Department of Surgical Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa" ], "article_type": "other", "arxiv": null, "author_total": 26, "authors": [ { "affs": [ 0 ], "name": "Marli Conradie-Smit" }, { "affs": [ 1 ], "name": "Wayne May" }, { "affs": [ 2 ], "name": "Clayton Arendse" }, { "affs": [ 3 ], "name": "Jason Bantjes" }, { "affs": [ 4 ], "name": "Zaheer Bayat" }, { "affs": [ 5 ], "name": "Elna Barnard" }, { "affs": [ 6 ], "name": "Sindeep Bhana" }, { "affs": [ 7 ], "name": "Nomathemba Chandiwana" }, { "affs": [ 8 ], "name": "Annibale Cois" }, { "affs": [ 9 ], "name": "Paula N. Diab" }, { "affs": [ 10 ], "name": "Zodwa Dire" }, { "affs": [ 1 ], "name": "Virginia R. Fourie" }, { "affs": [ 11 ], "name": "Julia H. Goedecke" }, { "affs": [ 12 ], "name": "Jocelyn Hellig" }, { "affs": [ 13 ], "name": "Zachary Koto" }, { "affs": [ 14 ], "name": "Kathleen Mawson" }, { "affs": [ 15 ], "name": "Makama Andries Monyeki" }, { "affs": [ 16 ], "name": "Angela Murphy" }, { "affs": [ 17 ], "name": "Christina Nieuwoudt" }, { "affs": [ 18 ], "name": "Marisa Noeth" }, { "affs": [ 19 ], "name": "Nicole Pearce" }, { "affs": [ 20 ], "name": "Joanna Skelton" }, { "affs": [ 21 ], "name": "Thinus (JGM) Smit" }, { "affs": [ 19, 22, 23 ], "name": "Sanjeev Sockalingam" }, { "affs": [ 24 ], "name": "Francois H. van Zyl" }, { "affs": [ 25 ], "name": "Jeanne Lubbe" } ], "bibtex": "https://research.draconitic.com/paper/4bsmj5wtan34k.bib", "cited_by": 0, "doi": "10.3389/fendo.2026.1875018", "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13696233/", "id": "4bsmj5wtan34k", "issns": [ "1664-2392" ], "landing_url": "https://doi.org/10.3389/fendo.2026.1875018", "language": "en", "licence": "CC-BY-4.0", "licence_label": "CC BY 4.0", "licence_source": "article", "licence_url": "https://creativecommons.org/licenses/by/4.0/", "metadata_licence": null, "native_subjects": [ [ "heading", "Policy and Practice Reviews" ], [ "openalex", "2739|Obesity, Physical Activity, Diet" ] ], "openalex": "W7221469627", "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13696233/pdf/?tool=EBI", "pmcid": "PMC13696233", "pmid": "42935529", "published": "2026-10-12", "publisher": "Frontiers Media SA", "ris": "https://research.draconitic.com/paper/4bsmj5wtan34k.ris", "sources": [ { "first_seen": "2026-10-30T12:17:37Z", "native_id": "PMC13696233", "source": "pmc", "url": "https://doi.org/10.3389/fendo.2026.1875018" }, { "first_seen": "2026-10-30T12:20:20Z", "native_id": "10.3389/fendo.2026.1875018", "source": "crossref", "url": "https://www.frontiersin.org/articles/10.3389/fendo.2026.1875018/full" }, { "first_seen": "2026-10-30T12:21:25Z", "native_id": "PMC:PMC13696233", "source": "europepmc", "url": "https://europepmc.org/article/PMC/PMC13696233" } ], "subjects": [ { "field": "medicine", "origin": "openalex:2739|Obesity, Physical Activity, Diet", "subfield": "epidemiology-public-health" } ], "title": "Obesity in adults: overview of a clinical practice guideline for South Africa", "title_text": "Obesity in adults: overview of a clinical practice guideline for South Africa", "type": "peer-reviewed", "updated_at": "2026-10-30T12:33:36Z", "url": "https://research.draconitic.com/paper/4bsmj5wtan34k", "venue": "Frontiers in Endocrinology", "versions": [] }