{
  "abstract": "Infective endocarditis (IE) is a potentially fatal condition. Early consultation with the nearest IE team and timely referral in the event of complications are recommended. This study investigated the association between receiving care in a reference centre and one-year mortality among patients with IE. Patients with definite IE enrolled in the EI 2008 cohort, a prospective population based-study, were categorised into three groups: 1) initially admitted to a reference centre (R); 2) initially admitted to a nonreference centre and subsequently referred to a reference centre (NR-R); and 3) exclusively managed in a nonreference centre (NR). Cox models were used for analysis. In our sample, 496 patients (279 R, 160 NR-R, and 57 NR) were included. Patients in the R and NR-R groups were younger and had a higher rate of indications for cardiac surgery. Overall, 142 patients (28.6%) died during follow-up. Care in a reference centre at any point was not associated with one-year mortality (crude-HR [95% CI]: 0.87 [0.57–1.33], p=0.518; adjusted-HR 0.98 [0.62–1.56], p=0.933). Further adjustment for valve surgery did not affect these results (adjusted HR 0.95 [0.59–1.53], p=0.831). Management at a reference centre was not associated with one-year mortality.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "name": "Benjamin Lefèvre"
    },
    {
      "name": "Marie-Line Erpelding"
    },
    {
      "name": "Yoann Dominique"
    },
    {
      "name": "Bruno Hoen"
    },
    {
      "name": "François Alla"
    },
    {
      "name": "Xavier Duval"
    },
    {
      "name": "François Vandenesch"
    },
    {
      "name": "Vincent Le Moing"
    },
    {
      "name": "Pierre Tattevin"
    },
    {
      "name": "Catherine Chirouze"
    },
    {
      "name": "Christine Selton-Suty"
    },
    {
      "name": "Nelly Agrinier"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4d4aqchqh26sy.bib",
  "cited_by": 0,
  "doi": "10.1038/s41598-026-64383-1",
  "fulltext_url": null,
  "id": "4d4aqchqh26sy",
  "issns": [
    "2045-2322"
  ],
  "landing_url": "https://hal.science/hal-05756911v1",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.mhep"
    ],
    [
      "hal",
      "1.sdv.spee"
    ],
    [
      "hal",
      "2.sdv.mhep.csc"
    ],
    [
      "hal",
      "2.sdv.mhep.mi"
    ],
    [
      "openalex",
      "2713|Infective Endocarditis Diagnosis and Management"
    ]
  ],
  "openalex": "W7204478548",
  "pdf_url": "https://hal.science/hal-05756911/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-27",
  "publisher": "Nature Publishing Group",
  "ris": "https://research.draconitic.com/paper/4d4aqchqh26sy.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:36Z",
      "native_id": "hal-05756911",
      "source": "hal",
      "url": "https://hal.science/hal-05756911v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "medicine",
      "origin": "hal:2.sdv.mhep.csc",
      "subfield": "cardiovascular"
    },
    {
      "field": "medicine",
      "origin": "hal:1.sdv.spee",
      "subfield": "epidemiology-public-health"
    },
    {
      "field": "medicine",
      "origin": "hal:2.sdv.mhep.mi",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Admission to a referral centre and one-year mortality among patients with infective endocarditis in a French multicentre cohort",
  "title_text": "Admission to a referral centre and one-year mortality among patients with infective endocarditis in a French multicentre cohort",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:36Z",
  "url": "https://research.draconitic.com/paper/4d4aqchqh26sy",
  "venue": "Scientific Reports",
  "versions": []
}