{
  "abstract": "BACKGROUND Standard screening mammogram views focus on the lateral and posterior breast tissues; the view that best visualizes the intermammary area, the 90-degree lateral or cleavage view, is not typically performed. The limited field of view of mammogram increases the importance of additional imaging with CT, ultrasound, and MRI as a tool in diagnosing neoplasm in the intermammary area. To date, intermammary primary breast carcinoma has been reported only a few times in the literature, and none of these described direct sternal invasion at presentation. CASE REPORT An 85-year-old woman with a past medical history of follicular non-Hodgkin lymphoma treated with bendamustine-rituximab in 2017 (without chest radiation) and significant family history of breast cancer presented to our clinic 2 months after noticing a hard, non-tender nodule on her sternum. She had undergone a routine screening mammogram 8 months prior, which was unremarkable. Subsequent diagnostic workup including targeted ultrasound, and PET-CT identified a hypermetabolic presternal mass. Notably, diagnostic mammography 8 months after the initial screening mammogram also failed to properly visualize the lesion. Biopsy confirmed ER+/PR+, HER2- adenocarcinoma consistent with breast origin. Despite negative initial staging for distant metastasis, pathological examination after resection revealed direct invasion into the sternum, necessitating partial sternectomy. CONCLUSIONS This case highlights a rare intermammary presentation of breast carcinoma with direct sternal invasion, a feature not previously reported. It emphasizes the blind spot of standard screening mammography in the medial breast/cleavage area and the necessity of targeted imaging for palpable parasternal masses, even in the setting of recent negative screens.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Internal Medicine, Creighton University School of Medicine, Phoenix, AZ, USA."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Rachel Deming"
    },
    {
      "affs": [
        0
      ],
      "name": "Michael Fei",
      "orcid": "0009-0001-0576-2413"
    },
    {
      "affs": [
        0
      ],
      "name": "Harsha Choudary Pudhota"
    },
    {
      "affs": [
        0
      ],
      "name": "Sonal P Haerter"
    },
    {
      "affs": [
        0
      ],
      "name": "Moustafa Hazin"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4e4gket0d5mg2.bib",
  "cited_by": 0,
  "doi": "10.12659/ajcr.953831",
  "fulltext_url": "https://europepmc.org/articles/PMC13685571",
  "id": "4e4gket0d5mg2",
  "issns": [
    "1941-5923"
  ],
  "landing_url": "https://europepmc.org/article/MED/42876016",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2734|Breast Lesions and Carcinomas"
    ]
  ],
  "openalex": "W7204591810",
  "pdf_url": "https://europepmc.org/articles/PMC13685571?pdf=render",
  "pmcid": "PMC13685571",
  "pmid": "42876016",
  "published": "2026-10-15",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4e4gket0d5mg2.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:46Z",
      "native_id": "MED:42876016",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42876016"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2734|Breast Lesions and Carcinomas",
      "subfield": "general"
    }
  ],
  "title": "Primary Intermammary Breast Carcinoma Presenting With Direct Sternal Invasion: A Diagnostic Pitfall of Standard Screening Mammography.",
  "title_text": "Primary Intermammary Breast Carcinoma Presenting With Direct Sternal Invasion: A Diagnostic Pitfall of Standard Screening Mammography.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:46Z",
  "url": "https://research.draconitic.com/paper/4e4gket0d5mg2",
  "venue": "The American journal of case reports",
  "versions": []
}