{
  "abstract": "Metabolic disorders are increasingly linked to epigenetic alterations. SWI/SNF chromatin remodeling complexes have emerged as critical modulators of metabolic homeostasis. In this review, we focus on the tissue-specific biological function of SWI/SNF complexes in the pancreas, liver, adipose tissue, and heart, and highlight the dysregulation of chromatin remodeling in metabolic disease progression. Lastly, we discuss therapeutic opportunities targeting chromatin remodeling mechanisms in metabolic disorders.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Scottsdale, AZ, USA.",
    "Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Scottsdale, AZ, USA. Wei.Zong@mayo.edu.",
    "Division of Endocrinology, Mayo Clinic Arizona, Scottsdale, AZ, USA. Wei.Zong@mayo.edu."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Faiz Ur Rahman"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Zong Wei",
      "orcid": "0000-0002-4691-0101"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4ea0e18yv08by.bib",
  "cited_by": 0,
  "doi": "10.1038/s44324-026-00137-x",
  "fulltext_url": "https://europepmc.org/articles/PMC13728216",
  "id": "4ea0e18yv08by",
  "issns": [
    "2948-2828"
  ],
  "landing_url": "https://europepmc.org/article/MED/42972009",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Review"
    ],
    [
      "openalex",
      "1312|Chromatin Remodeling and Cancer"
    ]
  ],
  "openalex": "W7225104664",
  "pdf_url": "https://europepmc.org/articles/PMC13728216?pdf=render",
  "pmcid": "PMC13728216",
  "pmid": "42972009",
  "published": "2026-11-02",
  "publisher": "Nature Publishing Group",
  "ris": "https://research.draconitic.com/paper/4ea0e18yv08by.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T15:20:43Z",
      "native_id": "MED:42972009",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42972009"
    },
    {
      "first_seen": "2026-11-06T12:23:56Z",
      "native_id": "PMC13728216",
      "source": "pmc",
      "url": "https://doi.org/10.1038/s44324-026-00137-x"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Chromatin Remodeling and Cancer",
      "subfield": "molecular-biology"
    }
  ],
  "title": "SWI/SNF chromatin remodeling complexes in metabolic disorders: integrating tissue-specific epigenetic mechanisms.",
  "title_text": "SWI/SNF chromatin remodeling complexes in metabolic disorders: integrating tissue-specific epigenetic mechanisms.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:23:56Z",
  "url": "https://research.draconitic.com/paper/4ea0e18yv08by",
  "venue": "Npj metabolic health and disease",
  "versions": []
}