{
  "abstract": "Patients with inflammatory bowel disease (IBD) have a higher risk of developing colorectal cancer (CRC) compared with the general population. This increased risk is mainly related to chronic colonic inflammation and is influenced by factors such as disease duration, disease extent, family history of CRC, and the presence of primary sclerosing cholangitis (PSC). Although the incidence of CRC in IBD has decreased over recent decades, it remains an important cause of disease-related morbidity and mortality. CRC prevention in IBD extends beyond colonoscopic surveillance and includes high-quality endoscopic surveillance, early detection and appropriate treatment of dysplasia, and long-term control of intestinal inflammation through a personalized approach. This review summarizes current evidence on IBD-associated colorectal carcinogenesis and strategies for CRC prevention, with emphasis on risk stratification, optimization of endoscopic surveillance, dysplasia management, treat-to-target strategies and multidisciplinary management.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Gastroenterology and Endoscopy, IRCCS San Raffaele Hospital, 20132 Milan, Italy",
    "Department of Gastroenterology and Endoscopy, Faculty of Medicine and Surgery, Vita-Salute San Raffaele University, 20132 Milan, Italy"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Boris Nassera"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Lucia Centanni"
    },
    {
      "affs": [
        0
      ],
      "name": "Ferdinando D’Amico",
      "orcid": "0000-0002-8591-6995"
    },
    {
      "affs": [
        0
      ],
      "name": "Alessandra Zilli"
    },
    {
      "affs": [
        0
      ],
      "name": "Tommaso Lorenzo Parigi"
    },
    {
      "affs": [
        1
      ],
      "name": "Federica Furfaro",
      "orcid": "0000-0002-4308-7295"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Virginia Solitano"
    },
    {
      "affs": [
        0
      ],
      "name": "Mariangela Allocca"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Silvio Danese"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4fhegapdtvrv4.bib",
  "cited_by": 0,
  "doi": "10.3390/cancers18203272",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13702115/?tool=EBI",
  "id": "4fhegapdtvrv4",
  "issns": [
    "2072-6694"
  ],
  "landing_url": "https://www.mdpi.com/2072-6694/18/20/3272",
  "language": "eng",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1311|Inflammatory Bowel Disease"
    ]
  ],
  "openalex": "W7221544413",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13702115/pdf/?tool=EBI",
  "pmcid": "PMC13702115",
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/4fhegapdtvrv4.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:58Z",
      "native_id": "10.3390/cancers18203272",
      "source": "crossref",
      "url": "https://www.mdpi.com/2072-6694/18/20/3272"
    },
    {
      "first_seen": "2026-10-30T12:21:31Z",
      "native_id": "PMC:PMC13702115",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13702115"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1311|Inflammatory Bowel Disease",
      "subfield": "genetics-genomics"
    }
  ],
  "title": "Colorectal Cancer in Inflammatory Bowel Disease: How to Minimize the Risk",
  "title_text": "Colorectal Cancer in Inflammatory Bowel Disease: How to Minimize the Risk",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:31Z",
  "url": "https://research.draconitic.com/paper/4fhegapdtvrv4",
  "venue": "Cancers",
  "versions": []
}