{
  "abstract": "Background/Objectives: This study aimed to assess additional findings reported on fetal magnetic resonance imaging (MRI) after targeted neurosonography in fetuses with agenesis of the corpus callosum (ACC). Methods: This retrospective cohort included 129 singleton pregnancies with complete or partial ACC evaluated at a tertiary referral center between January 2020 and January 2023. All underwent fetal MRI within 7 days of neurosonography. Incremental findings were abnormalities not identified on the preceding examination. Final isolated or non-isolated classification incorporated both modalities. Results: MRI reported at least one incremental intracranial or craniofacial finding in 42/129 fetuses (32.6%). The most frequent findings were cerebellar hypoplasia (15/129, 11.6%), vermian agenesis (11/129, 8.5%), and arachnoid cysts (9/129, 7.0%). Final classification identified 71 isolated and 58 non-isolated cases. Among 77 tested fetuses, 15 had aneuploidy; the frequency was higher in non-isolated cases (14/37 versus 1/40; p < 0.001). Conclusions: MRI provided additional anatomical information after neurosonography in approximately one-third of this referral cohort. These findings support assessment beyond confirmation of ACC, but do not establish diagnostic accuracy, improved parental decisions, or long-term prognostic benefit.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Perinatology, Department of Obstetrics and Gynecology, Mardin Training and Research Hospital, Mardin 47100, Türkiye",
    "Division of Perinatology, Department of Obstetrics and Gynecology, Çukurova University Faculty of Medicine, Adana 01330, Türkiye",
    "Division of Perinatology, University of Health Sciences, Gaziantep City Hospital, Gaziantep 27060, Türkiye",
    "Division of Perinatology, Department of Obstetrics and Gynecology, Osmaniye State Hospital, Osmaniye 80000, Türkiye",
    "Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mardin Training and Research Hospital, Mardin 47100, Türkiye"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Serdar Aykut",
      "orcid": "0000-0002-6590-9982"
    },
    {
      "affs": [
        1
      ],
      "name": "İsmail Cüneyt Evrüke"
    },
    {
      "affs": [
        1
      ],
      "name": "Süleyman Cansun Demir",
      "orcid": "0000-0001-8331-9559"
    },
    {
      "affs": [
        2
      ],
      "name": "Aslıhan Kurt"
    },
    {
      "affs": [
        3
      ],
      "name": "Ahmet Zeki Nessar",
      "orcid": "0000-0003-2985-0212"
    },
    {
      "affs": [
        4
      ],
      "name": "Ayşe Büşra Önder",
      "orcid": "0000-0003-4170-3768"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4gttd1c26c8w3.bib",
  "cited_by": 0,
  "doi": "10.3390/jcm15218502",
  "fulltext_url": null,
  "id": "4gttd1c26c8w3",
  "issns": [
    "2077-0383"
  ],
  "landing_url": "https://www.mdpi.com/2077-0383/15/21/8502",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-02",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/4gttd1c26c8w3.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:21:42Z",
      "native_id": "10.3390/jcm15218502",
      "source": "crossref",
      "url": "https://www.mdpi.com/2077-0383/15/21/8502"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:F27",
      "subfield": "general"
    }
  ],
  "title": "Incremental Diagnostic Yield of Fetal MRI After Targeted Neurosonography in Fetuses with Agenesis of the Corpus Callosum: A Retrospective Cohort Study",
  "title_text": "Incremental Diagnostic Yield of Fetal MRI After Targeted Neurosonography in Fetuses with Agenesis of the Corpus Callosum: A Retrospective Cohort Study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T00:21:25Z",
  "url": "https://research.draconitic.com/paper/4gttd1c26c8w3",
  "venue": "Journal of Clinical Medicine",
  "versions": []
}