{
  "abstract": "Background: Body mass index may fail to identify adolescents with occult cardiometabolic abnormalities. Acanthosisnigricans and acrochordons may provide externally visible indicators of insulin resistance and metabolic risk.Methods: This prospective analytical study included 180 adolescents aged 10–18 years, comprising 90 with acanthosisnigricans and/or acrochordons and 90 controls. Dermatological examination, anthropometry, blood pressure, fasting glucose, HbA1c and lipid profile were assessed. The triglyceride-glucose index was calculated. Multivariable logistic regression and receiver operating characteristic analyses evaluated predictors of clustered cardiometabolic abnormalities.Results: Cardiometabolic abnormalities were present in 44.4% of adolescents with cutaneous markers versus 20.0% of controls (p<0.001). Among normal-BMI participants, marker-positive adolescents had significantly higher glucose, HbA1c, triglycerides, TyG index, waist-to-height ratio and systolic blood pressure and lower HDL-C. At least two abnormalities occurred in 50.0% versus 14.5%, respectively (p<0.001). Cutaneous markers independently predicted cardiometabolic risk (adjusted OR 2.74; 95% CI 1.31–5.73). TyG achieved an AUC of 0.79, while the combined model achieved 0.86.Conclusion: Cutaneous metabolic markers may identify cardiometabolic risk beyond BMI and facilitate targeted screening of apparently normal-weight adolescents.",
  "abstract_shown": true,
  "affiliations": [
    "Assistant Professor, Department of Dermatology, Venereology and Leprosy (DVL), Father Colombo Institute of Medical Sciences, Warangal.",
    "Associate Professor, department of Paediatrics, GSL Medical College, Rajahmundry"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Panduri Deepthi Naidu",
      "orcid": "0009-0006-2845-7426"
    },
    {
      "affs": [
        1
      ],
      "name": "Manasa Gundapaneni",
      "orcid": "0009-0006-1853-6964"
    },
    {
      "affs": [
        0
      ],
      "name": "Sangem Sagarika",
      "orcid": "0009-0007-6826-9400"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4hgskv01xm9nv.bib",
  "cited_by": 0,
  "doi": "10.67170/jmmdt.2026.v2i10.004",
  "fulltext_url": "https://jmmdt.jcpublications.in/article/skin-before-the-scale-acanthosis-nigricans-and-acrochordons-expose-cardiometabolic-risk-beyond-bmi-in-adolescents",
  "id": "4hgskv01xm9nv",
  "issns": [
    "3108-2866"
  ],
  "landing_url": "https://jmmdt.jcpublications.in/article/skin-before-the-scale-acanthosis-nigricans-and-acrochordons-expose-cardiometabolic-risk-beyond-bmi-in-adolescents",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R"
    ],
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      "openalex",
      "2708|Skin Diseases and Diabetes"
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  "pdf_url": "https://doi.org/10.67170/jmmdt.2026.v2i10.004",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-26",
  "publisher": "JC Publications",
  "ris": "https://research.draconitic.com/paper/4hgskv01xm9nv.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:47:19Z",
      "native_id": "4f657668efa74f7b8db5b7f09baa6b3f",
      "source": "doaj",
      "url": "https://jmmdt.jcpublications.in/article/skin-before-the-scale-acanthosis-nigricans-and-acrochordons-expose-cardiometabolic-risk-beyond-bmi-in-adolescents"
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    {
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      "url": "https://doi.org/10.67170/jmmdt.2026.v2i10.004"
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2708|Skin Diseases and Diabetes",
      "subfield": "general"
    }
  ],
  "title": "Skin Before the Scale: Acanthosis Nigricans and Acrochordons Expose Cardiometabolic Risk Beyond BMI in Adolescents",
  "title_text": "Skin Before the Scale: Acanthosis Nigricans and Acrochordons Expose Cardiometabolic Risk Beyond BMI in Adolescents",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:47:29Z",
  "url": "https://research.draconitic.com/paper/4hgskv01xm9nv",
  "venue": "Journal of Medicine, Pharmacology and Medical Devises Technology",
  "versions": []
}