{
  "abstract": "Background\n\nAcute pancreatitis is an important cause of morbidity and mortality among patients presenting to the emergency department with abdominal pain.Objectives\n\nIn this study, we aimed to compare the diagnostic performance of the Bedside Index for Severity in Acute Pancreatitis (BISAP) and Emergency Department SpO2, Age, and Systemic Inflammatory Response Syndrome (ED-SAS) score for predicting severe acute pancreatitis (SAP) in older patients diagnosed with acute pancreatitis in the emergency department. The predictive performances of inflammatory markers, including the neutrophil-to-lymphocyte ratio, systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune-inflammation value, were also evaluated.Design and setting\n\nThis retrospective cohort study was conducted at a tertiary hospital in Türkiye.Methods\n\nFactors associated with SAP were evaluated using univariate and multivariate binary logistic regression analyses; odds ratios with 95% confidence intervals were calculated.Results\n\nThe study included 400 older patients with acute pancreatitis (SAP group, n = 80; non-SAP group, n = 320). The neutrophil-to-lymphocyte ratio, SII, SIRI, pan-immune-inflammation value, ED-SAS score, and BISAP showed good discrimination for SAP, yielding area under the receiver operating characteristic curve values of 0.82, 0.83, 0.85, 0.86, 0.81, and 0.82, respectively. In the multivariate analysis, an SII of > 5796.25 (odds ratio, 13.59), SIRI of > 11.79 (odds ratio, 7.57), ED-SAS score of > 1 (odds ratio, 5.41), and BISAP of > 1 (odds ratio, 2.91) remained independently associated with SAP.Conclusion\n\nThe SII, SIRI, ED-SAS score, and BISAP may support early risk stratification for SAP in geriatric pancreatitis. These parameters should be interpreted alongside clinical assessment rather than used as stand-alone diagnostic criteria.",
  "abstract_shown": true,
  "affiliations": [
    "MD. Emergency Medicine Specialist, Department of Emergency Medicine, Konya Training and Research Hospital, Baskent University, Konya, Türkiye.",
    "MD. Associate Professor, Department of Emergency Medicine, Antalya Training and Research Hospital, Antalya, Türkiye.",
    "PhD. Assistant Professor, Faculty of Medicine, Department of Biostatistics and Medical Informatics, Atlas University, Istanbul, Türkiye.",
    "MD. Emergency Medicine Specialist, Department of Emergency Medicine, Antalya Training and Research Hospital, Antalya, Türkiye."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Nafis Vural",
      "orcid": "0000-0002-3551-201X"
    },
    {
      "affs": [
        1
      ],
      "name": "Murat Duyan",
      "orcid": "0000-0002-6420-3259"
    },
    {
      "affs": [
        2
      ],
      "name": "Elif Ertas",
      "orcid": "0000-0003-1827-4862"
    },
    {
      "affs": [
        3
      ],
      "name": "Hasan Can Guven",
      "orcid": "0000-0001-5576-4911"
    },
    {
      "affs": [
        1
      ],
      "name": "Mehmet Akcimen",
      "orcid": "0000-0002-5241-9087"
    },
    {
      "affs": [
        3
      ],
      "name": "Osman Gürsoy Unal",
      "orcid": "0000-0002-3532-2240"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4j58x4353ph7c.bib",
  "cited_by": 0,
  "doi": "10.1590/1516-3180.2026.3603.14082026",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13705630/?tool=EBI",
  "id": "4j58x4353ph7c",
  "issns": [
    "1516-3180",
    "1806-9460"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13705630",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2746|Pancreatitis Pathology and Treatment"
    ]
  ],
  "openalex": "W7223355537",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13705630/pdf/?tool=EBI",
  "pmcid": "PMC13705630",
  "pmid": "42961290",
  "published": "2026-10-23",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4j58x4353ph7c.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:25Z",
      "native_id": "PMC:PMC13705630",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13705630"
    },
    {
      "first_seen": "2026-11-01T00:20:50Z",
      "native_id": "MED:42961290",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42961290"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Pancreatitis Pathology and Treatment",
      "subfield": "surgery"
    }
  ],
  "title": "Associations between the development of severe acute pancreatitis and the risk scores on admission and inflammatory biomarkers in older patients: a retrospective cohort study",
  "title_text": "Associations between the development of severe acute pancreatitis and the risk scores on admission and inflammatory biomarkers in older patients: a retrospective cohort study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T03:21:21Z",
  "url": "https://research.draconitic.com/paper/4j58x4353ph7c",
  "venue": "Sao Paulo medical journal = Revista paulista de medicina",
  "versions": []
}