{
  "abstract": "Background: The present study explored the association between the Chinese visceral adiposity index (CVAI) and lipid accumulation product (LAP) and hypertension in type 2 diabetes mellitus (T2DM) subjects.\n\nMethods: A total of 4,155 T2DM individuals were enrolled from the Second Hospital of Shijiazhuang in this cross-sectional investigation. We employed multivariable logistic regression, restricted cubic spline (RCS) modeling, threshold effect assessment, and stratified subgroup analyses. Missing covariates were addressed through multiple imputation, while complete-case data were used for sensitivity evaluation.\n\nResults: Among 4,155 participants (68.5% hypertensive), CVAI and LAP were positively associated with hypertension (P for trend < 0.001). Q4 vs. Q1 OR was 3.27 (95% CI: 2.66–4.02) for CVAI and 3.01 (95% CI: 2.43–3.72) for LAP. RCS evaluation demonstrated a significant nonlinear relationship between LAP and hypertension (P for non-linearity < 0.001), identifying a threshold value of 44.187 (95% CI: 42.141–46.233). CVAI showed linear associations in both sexes (P for non-linearity: 0.177 males, 0.055 females). Subgroup analyses showed consistent associations across strata (all P for interaction > 0.05).\n\nConclusions: CVAI and LAP are associated with hypertension in T2DM patients. LAP exhibits a nonlinear relationship with a threshold effect at approximately 44.2.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Endocrinology, The Second Hospital of Shijiazhuang",
    "Department of Orthopedics, The Armed Police Forces Hospital of Shandong"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yuwei Xing"
    },
    {
      "affs": [
        1
      ],
      "name": "Yishan Yin"
    },
    {
      "affs": [
        0
      ],
      "name": "Qianqian Zhao"
    },
    {
      "affs": [
        0
      ],
      "name": "Lili Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "Xian Xiu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4jbqy5nn02rp3.bib",
  "cited_by": 0,
  "doi": "10.3389/fendo.2026.1998153",
  "fulltext_url": null,
  "id": "4jbqy5nn02rp3",
  "issns": [
    "1664-2392"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fendo.2026.1998153/full",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2712|Diabetes, Cardiovascular Risks, and Lipoproteins"
    ]
  ],
  "openalex": "W7223802223",
  "pdf_url": "https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2026.1998153/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-27",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/4jbqy5nn02rp3.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:20Z",
      "native_id": "10.3389/fendo.2026.1998153",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fendo.2026.1998153/full"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2712|Diabetes, Cardiovascular Risks, and Lipoproteins",
      "subfield": "endocrinology-metabolism"
    }
  ],
  "title": "The association between obesity index and hypertension in type 2 diabetes: a cross-sectional study",
  "title_text": "The association between obesity index and hypertension in type 2 diabetes: a cross-sectional study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:20Z",
  "url": "https://research.draconitic.com/paper/4jbqy5nn02rp3",
  "venue": "Frontiers in Endocrinology",
  "versions": []
}