{
  "abstract": "Background: The Doppler-derived renal resistive index (RRI) reflects intrarenal vascular mechanics and systemic hemodynamics, offering prospective clinical value in nephropathy. Objectives: To investigate how RRI metrics correlate with serum levels of parathyroid hormone (PTH), calcium, and phosphorus across diabetic and non-diabetic chronic kidney disease (CKD) cohorts. Patients and methods: A cross-sectional cohort of 100 adult CKD subjects (50 diabetic kidney disease [DKD], 50 non-diabetic CKD) underwent standardized renal duplex ultrasonography alongside serum biochemical profiling for calcium, phosphate, and intact PTH. Results: In DKD patients, right-sided RRI (RRI-Rt) correlated directly with serum phosphate (r = 0.302, p = 0.033) and PTH (r = 0.479, p = 0.001). In non-diabetic CKD, RRI-Rt displayed an inverse relationship with total calcium (r = -0.662, p < 0.001) alongside robust positive relationships with phosphate (r = 0.787, p < 0.001) and PTH (r = 0.799, p < 0.001). Left-sided RRI (RRI-Lt) mirrored these bilateral associations. In the diabetic population, RRI-Lt was positively correlated with phosphorus (r = 0.354, p = 0.012) and PTH (r = 0.386, p = 0.006), while its correlation with calcium did not reach statistical significance. In the non-diabetic group, RRI-Lt showed a strong significant negative correlation with calcium (r = -0.645, p < 0.001), and strong significant positive correlations with phosphorus (r = 0.782, p < 0.001) and PTH (r = 0.797, p < 0.001). Conclusion: Bilateral RRI values parallel hyperphosphatemia and secondary hyperparathyroidism in both diabetic and non-diabetic renal populations, demonstrating enhanced magnitude in non-diabetic CKD.",
  "abstract_shown": true,
  "affiliations": [
    "Internal Medicine, Faculty of Medicine, Minia University",
    "Department of Internal Medicine Faculty of Medicine -Minia University",
    "Internal Medicine Department, Faculty of Medicine, Minia University, Egypt",
    "internal medicine department, faculty of medicine, minia university",
    "internal medicine department/ Clinical Endocrinology unit, Faculty of medicine -Minia university, Eygpt.",
    "Radiology Department, Faculty of Medicine, Minia University, Minia, Egypt",
    "internal medicine department faculty of medicine minia univeristy"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hassan Mohi El-Din"
    },
    {
      "affs": [
        1
      ],
      "name": "Amal Helmy"
    },
    {
      "affs": [
        2
      ],
      "name": "Maha Kahlawy"
    },
    {
      "affs": [
        3
      ],
      "name": "Aml Azzam"
    },
    {
      "affs": [
        4
      ],
      "name": "Shreen Mohamed"
    },
    {
      "affs": [
        5
      ],
      "name": "Tamer El Zaeem"
    },
    {
      "affs": [
        6
      ],
      "name": "fatmaa kamel"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4k492h0v8bqhj.bib",
  "cited_by": 0,
  "doi": "10.21608/mjmr.2026.536418.2404",
  "fulltext_url": "https://mjmr.journals.ekb.eg/article_534223.html",
  "id": "4k492h0v8bqhj",
  "issns": [
    "2682-4558"
  ],
  "landing_url": "https://doi.org/10.21608/mjmr.2026.536418.2404",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "2727|Chronic Kidney Disease and Diabetes"
    ]
  ],
  "openalex": "W7222879370",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-25",
  "publisher": "Minia University, Faculty of Medicine",
  "ris": "https://research.draconitic.com/paper/4k492h0v8bqhj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:12Z",
      "native_id": "39c5e4a26cec4334abed21cd39eb92ec",
      "source": "doaj",
      "url": "https://doi.org/10.21608/mjmr.2026.536418.2404"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2727|Chronic Kidney Disease and Diabetes",
      "subfield": "general"
    }
  ],
  "title": "Comparative Evaluation of Renal Resistive Index and Serum Calcium, Phosphorus, and Parathyroid Hormone Levels in Diabetic and Non-Diabetic Kidney Disease",
  "title_text": "Comparative Evaluation of Renal Resistive Index and Serum Calcium, Phosphorus, and Parathyroid Hormone Levels in Diabetic and Non-Diabetic Kidney Disease",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:12Z",
  "url": "https://research.draconitic.com/paper/4k492h0v8bqhj",
  "venue": "Minia Journal of Medical Research",
  "versions": []
}