{
  "abstract": "Selectivity control in aerobic oxidation reactions containing several oxidizable functional groups remains challenging. Herein, we show that the chemoselectivity of a Zr-MOF/quinone 2 multicatalytic platform can be controlled through modulation of the organic redox co-catalyst. In contrast to previously reported Zr-MOF-808/(hydro)quinone combinations that promote direct oxidation of anilines or thiols, Zr-MOF-808/1,8-dichloroanthraquinone unlocks a different reaction pathway to selectively oxidize primary alcohols in the presence of aromatic diamines and aminothiophenols. This pathway enables the one-pot synthesis of 2-substituted benzimidazoles and benzothiazoles under atmospheric air. Mechanistic experiments support coupled catalytic cycles in which Lewis-acidic Zr sites facilitate quinone-mediated alcohol oxidation, while the MOF/semiquinone interface regenerates the oxidized mediator using oxygen. This method furnishes a highly sustainable synthesis of 31 benzimidazole and benzothiazole products, permitting recovery and reuse of both catalytic components.",
  "abstract_shown": true,
  "affiliations": [
    "Wallenberg Initiative Materials Science for Sustainability",
    "Department of Chemistry, Stockholm University",
    "Department of Chemistry",
    "Stockholm University",
    "Department of Physics, Chemistry, and Biology (IFM",
    "Linköping University"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0,
        1,
        2,
        3
      ],
      "name": "Juan Camilo Arango-Daza"
    },
    {
      "affs": [
        0,
        1,
        2,
        3
      ],
      "name": "Spandan Hati"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Sakarn Khamkaeo"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Yuttapoom Puttisong"
    },
    {
      "affs": [
        0,
        1,
        2,
        3
      ],
      "name": "Miguel A. Rivero-Crespo",
      "orcid": "0000-0002-3860-0947"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4k7c4sxyz063c.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010252/v1",
  "fulltext_url": null,
  "id": "4k7c4sxyz063c",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010252/v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1604|Metal-Organic Frameworks: Synthesis and Applications"
    ]
  ],
  "openalex": "W7221569406",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010252/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-12",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/4k7c4sxyz063c.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:22Z",
      "native_id": "10.26434/chemrxiv.15010252",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010252/v2"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1604|Metal-Organic Frameworks: Synthesis and Applications",
      "subfield": "inorganic"
    }
  ],
  "title": "Zr-MOF/Quinone Multicatalysis Enables Programmable Aerobic Synthesis of Benzimidazoles",
  "title_text": "Zr-MOF/Quinone Multicatalysis Enables Programmable Aerobic Synthesis of Benzimidazoles",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:26Z",
  "url": "https://research.draconitic.com/paper/4k7c4sxyz063c",
  "venue": "ChemRxiv",
  "versions": []
}