{
  "abstract": "Polysaccharides in Morchella esculenta exhibit notable prebiotic potential; however, the gut microbial metabolic responses to high-pressure extracted polysaccharides (HPPs) remain poorly understood. Cooked M. esculenta powders (CMPs) were included to represent the commonly consumed form and the intact mushroom matrix. This study investigated gut microbiota-targeted metabolic functions in response to CMPs and HPPs followed by in vitro gastrointestinal digestion and fermentation. High-pressure extraction elevated β -glucan content (42.36 ± 1.51%) and generated a carbohydrate-enriched fraction of 325 kDa. During digestion, HPPs underwent a reduction in molecular weight and changes in monosaccharide composition, resulting in enhanced digestibility (35.24 ± 1.73%). The HPPs promoted short-chain fatty acids production and selectively modulated gut microbiota, such as Bacteroides, Bifidobacterium , and Acidaminococcus . Predictive functional profiling suggested enrichment in carbohydrate metabolism pathways, particularly galactose, mannose, propanoate and butanoate metabolism. This study serves the development of M. esculenta as functional food ingredients in regulating gut microbiota composition.",
  "abstract_shown": true,
  "affiliations": [
    "Interdisciplinary Graduate Program in Bioscience, Faculty of Science, Kasetsart University, Bangkok, 10900, Thailand",
    "Department of Food Science and Technology, Faculty of Agro-Industry, Kasetsart University, Bangkok, 10900, Thailand",
    "School of Food Science and Engineering, Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Hainan University, Haikou, 570228, China",
    "Department of Biotechnology and Biomedicine, Technical University of Denmark, Søltofts Plads, Building 223, Kongens Lyngby, 2800, Denmark",
    "Department of Food Science and Technology, Faculty of Agro-Industry, Kasetsart University, Bangkok, 10900, Thailand; Corresponding author."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Bingshu Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Yuke He"
    },
    {
      "affs": [
        1
      ],
      "name": "Putsawee Tomtong"
    },
    {
      "affs": [
        2
      ],
      "name": "Ruimin Wang"
    },
    {
      "affs": [
        3
      ],
      "name": "Solange I. Mussatto"
    },
    {
      "affs": [
        4
      ],
      "name": "Suvimol Charoensiddhi"
    },
    {
      "name": "Wanwipa Vongsangnak"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4k7fhpearqzwq.bib",
  "cited_by": 0,
  "doi": "10.1016/j.fhfh.2026.100312",
  "fulltext_url": "http://www.sciencedirect.com/science/article/pii/S2667025926000476",
  "id": "4k7fhpearqzwq",
  "issns": [
    "2667-0259"
  ],
  "landing_url": "https://doi.org/10.1016/j.fhfh.2026.100312",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC620-627"
    ],
    [
      "lcc",
      "TX341-641"
    ],
    [
      "openalex",
      "2736|Fungal Biology and Applications"
    ]
  ],
  "openalex": "W7222821363",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/4k7fhpearqzwq.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:47:21Z",
      "native_id": "975e0a50561048b2b309e3fa85277b4b",
      "source": "doaj",
      "url": "https://doi.org/10.1016/j.fhfh.2026.100312"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2736|Fungal Biology and Applications",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Elucidating gut microbiota-targeted carbohydrate metabolic functions by high-pressure extracted polysaccharides from",
  "title_text": "Elucidating gut microbiota-targeted carbohydrate metabolic functions by high-pressure extracted polysaccharides from",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:47:21Z",
  "url": "https://research.draconitic.com/paper/4k7fhpearqzwq",
  "venue": "Food Hydrocolloids for Health",
  "versions": []
}