{
  "abstract": "Objective: This study aims to assess the comprehensive national trends in deaths related to pneumonia and AMI in the US from 1999 to 2023.\n\nMethods: CDC wonder multiple cause of death database was used to extract data of elderly (≥65 years) with pneumonia and AMI as main or contributing cause of death. Age-Adjusted Mortality Rates (AAMRs) per 100,000 population were calculated. Trends were stratified by sex, race/ethnicity, state, urban-rural classification, census region, ten-year age group, and place of death.\n\nResults: A total of 186,411 deaths associated with pneumonia and AMI during 1999-2023 were identified. The cumulative AAMR was 17.76 during 1999-2020, and 14.2 during 2021-2023. A significant decline in AAMR was found through the study period (AAPC:-4.26, 95% CI −6.71 to -1.74). The AAMR of men was higher than women, and the decrease of AAMR was steeper in women (AAPC:-4.38, 95% CI -6.78 to -1.92 among women vs. -4.07, 95% CI -5.68 to -2.43 among men). NH American Indian or Alaska Native has the highest AAMR, while NH Asian or Pacific Islander had the lowest AAPC (-5.03, 95% CI -7.95 to -2.02). Non-metropolitan had higher AAMR (22.93 vs. 16.59) and AAPC (-1.69 vs. -3.51) than metropolitan. South region showed the highest AAMR and AAPC compared to other census regions.\n\nConclusions: The AAMR per 100,000 of pneumonia and AMI decreased among older adults in the US during 1999-2023, with higher mortality burden among men, NH American Indian or Alaska Native, rural area, and South region.",
  "abstract_shown": true,
  "affiliations": [
    "Organ Transplantation Center, The Affiliated Hospital of Qingdao University , , ,",
    "Department of Orthopaedics, The Affiliated Hospital of Qingdao University , , ,",
    "Department of Hand and Foot, Microsurgery, The Affiliated Hospital of Qingdao University , , ,",
    "The First Clinical Medical College, Shandong University of Traditional Chinese Medicine , , ,"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Shuai Feng"
    },
    {
      "affs": [
        0
      ],
      "name": "Lianghao Zhang"
    },
    {
      "affs": [
        1
      ],
      "name": "Lin Quan"
    },
    {
      "affs": [
        1
      ],
      "name": "Nannan Jiang"
    },
    {
      "affs": [
        2
      ],
      "name": "Ziyi Zhao"
    },
    {
      "affs": [
        3
      ],
      "name": "Hongxiang Ji"
    },
    {
      "affs": [
        0
      ],
      "name": "Chuanshen Xu"
    },
    {
      "affs": [
        0
      ],
      "name": "Jinquan Liu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4kdd59tt4r3r8.bib",
  "cited_by": 0,
  "doi": "10.3389/fcvm.2026.1913867",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661469/?tool=EBI",
  "id": "4kdd59tt4r3r8",
  "issns": [
    "2297-055X"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13661469",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2713|Healthcare Systems and Public Health"
    ]
  ],
  "openalex": "W7214939368",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661469/pdf/?tool=EBI",
  "pmcid": "PMC13661469",
  "pmid": null,
  "published": "2026-09-30",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/4kdd59tt4r3r8.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:20Z",
      "native_id": "PMC:PMC13661469",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13661469"
    },
    {
      "first_seen": "2026-10-30T12:20:10Z",
      "native_id": "10.3389/fcvm.2026.1913867",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fcvm.2026.1913867/full"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Healthcare Systems and Public Health",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Trends in mortality due to acute myocardial infarction and pneumonia among older adults in the U.S.: a CDC wonder analysis (1999-2023)",
  "title_text": "Trends in mortality due to acute myocardial infarction and pneumonia among older adults in the U.S.: a CDC wonder analysis (1999-2023)",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:10Z",
  "url": "https://research.draconitic.com/paper/4kdd59tt4r3r8",
  "venue": "Frontiers in cardiovascular medicine",
  "versions": []
}