{
  "abstract": "Background: Sodium-glucose cotransporter 2 inhibitors (SGLT2is) have been shown to decrease heart failure hospitalizations (HFHs) and cardiovascular (CV) death; however, Hispanic/Latino patients and methamphetamine (MA) users have been under-represented.\n\nProject Rationale: The purpose of this retrospective study was to assess CV outcomes in the Central Valley region of California within 12 months of starting a SGLT2i.\n\nProject Summary: Overall, 413 patients were included, with non-White patients and MA users accounting for 72% and 27% of the population, respectively. The composite CV outcome occurred in 86 of 413 patients (20.8%), 22% of Whites and 19%-27% of non-Whites. Significantly reduced HFH rates were observed in the overall population and subgroups after 1 year of starting SGLT2i. Reduced left ventricular ejection fraction, prior HFH, and MA use predicted CV outcomes, though the retrospective nature of this analysis limits causal inference.\n\nTake-Home Message: MA use, prior HFH, and reduced left ventricular ejection fraction predicted CV outcomes, irrespective of ethnicity.",
  "abstract_shown": true,
  "affiliations": [
    "St Joseph's Medical Center, Cardiovascular Disease Fellowship, Department of Medicine/Division of Cardiology, Stockton, California, USA",
    "San Joaquin General Hospital, Internal Medicine Department, French Camp, California, USA",
    "Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, California, USA"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Sun Yong Lee"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Tiffany Vu"
    },
    {
      "affs": [
        2
      ],
      "name": "Jessica Song"
    },
    {
      "affs": [
        1
      ],
      "name": "Mohsen Saadat"
    },
    {
      "affs": [
        2
      ],
      "name": "Taylor Thai"
    },
    {
      "affs": [
        2
      ],
      "name": "Rajkumar J. Sevak"
    },
    {
      "affs": [
        2
      ],
      "name": "Elisa Nguyen"
    },
    {
      "affs": [
        2
      ],
      "name": "Harnoor Gill"
    },
    {
      "affs": [
        1
      ],
      "name": "Cesfe Banola"
    },
    {
      "affs": [
        1
      ],
      "name": "Syung Min Jung"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4mjq440n887av.bib",
  "cited_by": 0,
  "doi": "10.1016/j.jaccas.2026.109454",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13728403/",
  "id": "4mjq440n887av",
  "issns": [
    "2666-0849"
  ],
  "landing_url": "https://doi.org/10.1016/j.jaccas.2026.109454",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Heart Failure and Cardiomyopathies"
    ],
    [
      "heading",
      "Quality Improvement Projects"
    ],
    [
      "openalex",
      "2705|Heart Failure Treatment and Management"
    ]
  ],
  "openalex": "W7213423342",
  "pdf_url": "https://www.jacc.org/doi/pdf/10.1016/j.jaccas.2026.109454?download=true",
  "pmcid": "PMC13728403",
  "pmid": "42752038",
  "published": "2026-09-16",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/4mjq440n887av.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:21:24Z",
      "native_id": "PMC13728403",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.jaccas.2026.109454"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Heart Failure Treatment and Management",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Cardiovascular Outcomes With Sodium-Glucose Cotransporter 2 Inhibitors in Ethnically Diverse Patients With Heart Failure",
  "title_text": "Cardiovascular Outcomes With Sodium-Glucose Cotransporter 2 Inhibitors in Ethnically Diverse Patients With Heart Failure",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:21:24Z",
  "url": "https://research.draconitic.com/paper/4mjq440n887av",
  "venue": "JACC Case Reports",
  "versions": []
}