{
  "abstract": "Objective. To evaluate the clinical utility of the neutrophil-to-lymphocyte ratio (NLR) for early prediction of severe acute pancreatitis (SAP) across admission, 24-hour, and 48-hour windows.\n\nMethods. Systematic review with meta-analytic synthesis of studies measuring NLR at admission and during the first two days, using random-effects and bivariate diagnostic-accuracy models.\n\nResults. Elevated admission NLR consistently tracked with subsequent severe disease and performed as well as – or better than – baseline laboratory indicators in emergency settings. Discrimination at presentation supported reliable early risk stratification, while day-1/day-2 trajectories maintained or enhanced sensitivity, enabling practical re-triage after initial management. Pooled accuracy estimates and hierarchical performance curves demonstrated good ability of NLR to distinguish severe from non-severe courses across cohorts and etiologic subgroups.\n\nConclusions. NLR is a simple, reproducible tool for early prediction of the severe course of acute pancreatitis; time-specific measurements with local threshold calibration and integration into standard clinical scores are recommended.",
  "abstract_shown": true,
  "affiliations": [
    "Surgical Center, Saint Paraskeva Medical Center, Lviv, Ukraine"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "S. M. Chooklin"
    },
    {
      "affs": [
        0
      ],
      "name": "S. S. Chuklin"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4n3b93afbn4rn.bib",
  "cited_by": 0,
  "doi": "10.26779/2786-832x.2026.5.96",
  "fulltext_url": "https://hirurgiya.com.ua/index.php/journal/article/view/1368",
  "id": "4n3b93afbn4rn",
  "issns": [
    "2786-832X",
    "2786-8311"
  ],
  "landing_url": "https://doi.org/10.26779/2786-832x.2026.5.96",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RD1-811"
    ],
    [
      "openalex",
      "2746|Pancreatitis Pathology and Treatment"
    ]
  ],
  "openalex": "W7223307600",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Liga-Inform ltd.",
  "ris": "https://research.draconitic.com/paper/4n3b93afbn4rn.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:56Z",
      "native_id": "75085c7e23de4e5e8efdd378d46cb0c1",
      "source": "doaj",
      "url": "https://doi.org/10.26779/2786-832x.2026.5.96"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Pancreatitis Pathology and Treatment",
      "subfield": "surgery"
    }
  ],
  "title": "Simple number, complicated answers: neutrophil-to-lymphocyte ratio in acute pancreatitis – a systematic review and meta-analysis",
  "title_text": "Simple number, complicated answers: neutrophil-to-lymphocyte ratio in acute pancreatitis – a systematic review and meta-analysis",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:56Z",
  "url": "https://research.draconitic.com/paper/4n3b93afbn4rn",
  "venue": "Український журнал клінічної хірургії",
  "versions": []
}