{
  "abstract": "The 21-valent pneumococcal conjugate vaccine (PCV21; CAPVAXIVE; Merck Sharp & Dohme) is the first pneumococcal conjugate vaccine (PCV) specifically designed for adults, targeting serotypes that currently cause disease in this population. PCV21 includes 11 serotypes not contained in any other approved PCV (9N, 15A, 15C, 16F, 17F, 20A, 23A, 23B, 24F, 31, and 35B), together with serotypes 3, 6A, 7F, 8, 10A, 11A, 12F, 19A, 22F, and 33F. PCV21 was approved by the Korean Ministry of Food and Drug Safety in August 27, 2025. The Adult Immunization Committee of the Korean Society of Infectious Diseases recommends one of the following options for all adults aged ≥65 years and for adults aged 19-64 years at increased risk of pneumococcal disease: a single dose of PCV21, a single dose of PCV20, or sequential PCV15 followed by PPSV23, with no stated preference among these options. When PCV21 or PCV20 is administered, no additional pneumococcal vaccination is required. Because PCV21 does not include serotype 4, in populations with a high incidence of serotype 4 disease, PCV20 alone or sequential PCV15 followed by PPSV23 may be preferentially considered.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.",
    "Division of Infectious Diseases, Department of Internal Medicine, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. ktkwon@knu.ac.kr.",
    "Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.",
    "Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.",
    "Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, Soonchunhyang University of Korea, Bucheon, Korea.",
    "Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.",
    "Department of Infectious Diseases, Ajou University School of Medicine, Suwon, Korea."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Joon Young Song",
      "orcid": "0000-0002-0148-7194"
    },
    {
      "affs": [
        1
      ],
      "name": "Ki Tae Kwon",
      "orcid": "0000-0003-4666-0672"
    },
    {
      "affs": [
        2
      ],
      "name": "Wan Beom Park",
      "orcid": "0000-0003-0022-9625"
    },
    {
      "affs": [
        0
      ],
      "name": "Ji Yun Noh",
      "orcid": "0000-0001-8541-5704"
    },
    {
      "affs": [
        3
      ],
      "name": "Sun Hee Park",
      "orcid": "0000-0001-5648-9237"
    },
    {
      "affs": [
        4
      ],
      "name": "Eun Ju Choo",
      "orcid": "0000-0003-2842-7041"
    },
    {
      "affs": [
        0
      ],
      "name": "Min Joo Choi",
      "orcid": "0000-0002-2739-0948"
    },
    {
      "affs": [
        5
      ],
      "name": "Jun Yong Choi",
      "orcid": "0000-0002-2775-3315"
    },
    {
      "affs": [
        6
      ],
      "name": "Jung Yeon Heo",
      "orcid": "0000-0002-6548-1939"
    },
    {
      "affs": [
        0
      ],
      "name": "Won Suk Choi",
      "orcid": "0000-0001-5874-4764"
    },
    {
      "name": "Committee of Adult Immunization in the Korean Society of Infectious Diseases"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4pxyxfrv898jz.bib",
  "cited_by": 0,
  "doi": "10.3947/ic.2026.0063",
  "fulltext_url": "https://europepmc.org/articles/PMC13655469",
  "id": "4pxyxfrv898jz",
  "issns": [
    "2093-2340",
    "2092-6448"
  ],
  "landing_url": "https://europepmc.org/article/MED/42847625",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2713|Pneumonia and Respiratory Infections"
    ]
  ],
  "openalex": "W7214064435",
  "pdf_url": "https://europepmc.org/articles/PMC13655469?pdf=render",
  "pmcid": "PMC13655469",
  "pmid": "42847625",
  "published": "2026-09-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4pxyxfrv898jz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:10Z",
      "native_id": "MED:42847625",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42847625"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Pneumonia and Respiratory Infections",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Recommendations for Adult Pneumococcal Vaccination in Korea: 2026 Update Incorporating the 21-Valent Pneumococcal Conjugate Vaccine.",
  "title_text": "Recommendations for Adult Pneumococcal Vaccination in Korea: 2026 Update Incorporating the 21-Valent Pneumococcal Conjugate Vaccine.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:10Z",
  "url": "https://research.draconitic.com/paper/4pxyxfrv898jz",
  "venue": "Infection & chemotherapy",
  "versions": []
}