{
  "abstract": "Background\n\nPressure assist ventilation (PAV) is considered superior to pressure support ventilation (PSV). We performed an updated systematic review and meta-analysis to evaluate comparative effectiveness in terms of weaning outcomes.Methods\n\nWe searched PubMed, Embase, and Cochrane for eligible randomized controlled trials (RCTs) published before October 2025 that directly compared clinical outcomes of PAV and PSV in mechanically ventilated adults. R program was used to calculate risk ratio (RR) and mean difference (MD) with 95% confidence intervals (CIs).Results\n\nAfter screening the titles, abstracts, and full texts, we included eight RCTs consisting of 1057 patients in our systematic review and meta-analysis. PAV was associated with a higher rate of weaning success as compared to PSV (RR: 1.09; 95% CI, 1.01-1.18; p = 0.03; I ² = 23%). PAV was associated with a lesser duration of ventilation (MD: -1.06; 95% CI, -1.82 to -0.29, p = 0.006; I ² = 0%) and intensive care unit (ICU) stay (MD: -1.49; 95% CI: -2.43 to -0.54, p = 0.002; I ² = 25%) as compared to PSV. However, no statistically significant benefit was observed for PAV over PSV with regard to rate of reintubation (RR: 0.82; 95%, CI: 0.58-1.16, p = 0.21, I ² = 0%) and mortality (RR: 0.89; 95% CI: 0.63-1.25 p = 0.4I ² = 30%).Conclusion\n\nPAV is superior to PSV for weaning, showing increased success and shorter duration of ventilation and ICU stays, though reintubation and mortality rates were similar.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Medicine Nishtar Medical University Multan Pakistan duhs.edu.pk.",
    "Department of Medicine Services Institute of Medical Sciences Lahore Pakistan sims.edu.pk.",
    "Department of Medicine King Edward Medical University Lahore Pakistan kemu.edu.pk.",
    "Mayo Clinic Rochester Minnesota USA mayo.edu.",
    "Department of Medicine MGM Medical College Navi Mumbai India mgmmedicalcollege.org.",
    "Department of Medicine Kist Medical College Lalitpur Nepal kistmcth.edu.np."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Muhammad Hassan Raza",
      "orcid": "0000-0002-6256-5213"
    },
    {
      "affs": [
        1
      ],
      "name": "Obaid Ur Rehman",
      "orcid": "0009-0000-8302-2173"
    },
    {
      "affs": [
        2
      ],
      "name": "Umad Ali",
      "orcid": "0009-0006-5192-1055"
    },
    {
      "affs": [
        3
      ],
      "name": "Aqsa Komel"
    },
    {
      "affs": [
        4
      ],
      "name": "Pratishruti",
      "orcid": "0009-0000-4283-7069"
    },
    {
      "affs": [
        2
      ],
      "name": "Talha Bin Kashif",
      "orcid": "0000-0002-4165-7784"
    },
    {
      "affs": [
        5
      ],
      "name": "Ajay Pandey",
      "orcid": "0009-0008-5477-9677"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4qcc8t20dgx2v.bib",
  "cited_by": 0,
  "doi": "10.1155/ccrp/7536067",
  "fulltext_url": "https://europepmc.org/articles/PMC13717589",
  "id": "4qcc8t20dgx2v",
  "issns": [
    "2090-1305",
    "2090-1313"
  ],
  "landing_url": "https://europepmc.org/article/MED/42959802",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "2740|Respiratory Support and Mechanisms"
    ]
  ],
  "openalex": "W7224171057",
  "pdf_url": "https://europepmc.org/articles/PMC13717589?pdf=render",
  "pmcid": "PMC13717589",
  "pmid": "42959802",
  "published": "2026-10-29",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/4qcc8t20dgx2v.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T00:20:50Z",
      "native_id": "MED:42959802",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42959802"
    },
    {
      "first_seen": "2026-11-02T12:21:53Z",
      "native_id": "PMC13717589",
      "source": "pmc",
      "url": "https://doi.org/10.1155/ccrp/7536067"
    }
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2740|Respiratory Support and Mechanisms",
      "subfield": "general"
    }
  ],
  "title": "Impact of Proportional Assist Ventilation Versus Pressure Support Ventilation on Adult Liberation From Mechanical Ventilation: A Revised Systematic Review and Meta-Analysis of RCTs.",
  "title_text": "Impact of Proportional Assist Ventilation Versus Pressure Support Ventilation on Adult Liberation From Mechanical Ventilation: A Revised Systematic Review and Meta-Analysis of RCTs.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:21:53Z",
  "url": "https://research.draconitic.com/paper/4qcc8t20dgx2v",
  "venue": "Critical care research and practice",
  "versions": []
}