{
  "abstract": "Centromeres are essential for chromosome segregation, yet their organization and evolution remain poorly understood in polyploid crops. We present the first complete telomere-to-telomere reference genome of Brassica napus cultivar Zhongshuang11 and characterize centromere architecture and evolution. We identify core satellite repeats that define centromeres and reveal extensive sequence polymorphism and structural divergence between subgenomes associated with polyploidization and domestication. We further uncover rDNA-enriched pericentromeres generated by recurrent chromosome rearrangements and propose a centromere evolutionary cycle model that explains how satellite repeats and transposons jointly shape centromere evolution.",
  "abstract_shown": true,
  "affiliations": [
    "College of Agronomy and Biotechnology, Southwest University, Chongqing, 400715, China.",
    "Yazhouwan National Laboratory, Sanya, 572025, China.",
    "College of Life Science and Technology, Guangxi University, Nanning, 530004, China.",
    "Engineering Research Center of Grain and Oil Crops in Southwest Mountain, Ministry of Education, Chongqing, China.",
    "Yazhouwan National Laboratory, Sanya, 572025, China. chenlingling@yzwlab.cn.",
    "College of Life Science and Technology, Guangxi University, Nanning, 530004, China. chenlingling@yzwlab.cn.",
    "College of Agronomy and Biotechnology, Southwest University, Chongqing, 400715, China. drlukun@swu.edu.cn.",
    "Engineering Research Center of Grain and Oil Crops in Southwest Mountain, Ministry of Education, Chongqing, China. drlukun@swu.edu.cn.",
    "College of Agronomy and Biotechnology, Southwest University, Chongqing, 400715, China. jmsong@swu.edu.cn.",
    "Engineering Research Center of Grain and Oil Crops in Southwest Mountain, Ministry of Education, Chongqing, China. jmsong@swu.edu.cn.",
    "Key Laboratory of Germplasm Innovation of Upper Yangtze River, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400715, China. jmsong@swu.edu.cn."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 17,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Xin-Dong Xu"
    },
    {
      "affs": [
        0
      ],
      "name": "Si-Ying Ye"
    },
    {
      "affs": [
        0
      ],
      "name": "Pei Wu"
    },
    {
      "affs": [
        0
      ],
      "name": "Yong-Qing Qian"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Zu-Wen Zhou"
    },
    {
      "affs": [
        0
      ],
      "name": "Yibo Chai"
    },
    {
      "affs": [
        0
      ],
      "name": "Ziyan Feng"
    },
    {
      "affs": [
        0
      ],
      "name": "Yingying Tan"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Jie Xiang"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Lijuan Wei"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Rui Wang"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Qingyuan Zhou"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Cunmin Qu"
    },
    {
      "affs": [
        0
      ],
      "name": "Jiana Li"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Ling-Ling Chen"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Kun Lu"
    },
    {
      "affs": [
        8,
        9,
        10
      ],
      "name": "Jia-Ming Song",
      "orcid": "0000-0002-6636-4152"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4qd0bm6q6xckh.bib",
  "cited_by": 1,
  "doi": "10.1186/s13059-026-04218-4",
  "fulltext_url": "https://europepmc.org/articles/PMC13721389",
  "id": "4qd0bm6q6xckh",
  "issns": [
    "1474-7596",
    "1474-760X"
  ],
  "landing_url": "https://europepmc.org/article/MED/42958420",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Brief Report"
    ],
    [
      "openalex",
      "1110|Chromosomal and Genetic Variations"
    ]
  ],
  "openalex": "W7171469236",
  "pdf_url": "https://europepmc.org/articles/PMC13721389?pdf=render",
  "pmcid": "PMC13721389",
  "pmid": "42958420",
  "published": "2026-07-27",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/4qd0bm6q6xckh.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T00:20:48Z",
      "native_id": "MED:42958420",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42958420"
    },
    {
      "first_seen": "2026-11-03T12:22:05Z",
      "native_id": "PMC13721389",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s13059-026-04218-4"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1110|Chromosomal and Genetic Variations",
      "subfield": "plant-biology"
    }
  ],
  "title": "A complete reference genome reveals genetic landscape of Brassica centromeres.",
  "title_text": "A complete reference genome reveals genetic landscape of Brassica centromeres.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:05Z",
  "url": "https://research.draconitic.com/paper/4qd0bm6q6xckh",
  "venue": "Genome biology",
  "versions": []
}