{
  "abstract": "Background\n\nRadiotherapy is a cornerstone in the management of localized and locally advanced prostate cancer. Three-dimensional conformal radiotherapy (3D-CRT) has been widely used, while intensity-modulated radiotherapy (IMRT) allows more conformal dose distribution and potentially better sparing of surrounding normal tissues. This retrospective study aimed to compare the dosimetric characteristics of IMRT and four-field 3D-CRT in patients with prostate cancer.\n\nMethods\n\nThis retrospective study included 63 patients with prostate cancer treated at Minya university and Ahmed Maher Teaching Hospital. Patients were divided into two treatment groups: 30 patients treated using four-field 3D-CRT and 33 patients treated using IMRT. All patients received a total prescribed dose of 70 Gy in 35 fractions. Treatment planning was performed using an Elekta radiotherapy system. Depending on clinical stage, treatment volumes included the prostate alone or the prostate with pelvic lymphatic regions. Dosimetric parameters for the target volume and organs at risk were evaluated and compared between the two techniques.\n\nResults\n\nThe dosimetric analysis demonstrated differences between IMRT and four-field 3D-CRT in target coverage and dose distribution, as well as in the radiation exposure of surrounding organs at risk. IMRT provided a more conformal dose distribution around the intended treatment volume while allowing improved dose optimization to adjacent normal tissues.\n\nConclusion\n\nIn this retrospective cohort, IMRT demonstrated dosimetric advantages compared with four-field 3D-CRT for prostate cancer radiotherapy. These findings support the use of IMRT when available to achieve improved treatment-plan conformity and normal-tissue sparing while maintaining adequate target coverage.",
  "abstract_shown": true,
  "affiliations": [
    "Oncology department Minya university",
    "department of clinical oncology",
    "Department of oncology, El-Minia faculty of medicine",
    "Clinical Oncology and Nuclear Medicine - Faculty of Medicine -Minia University, Egypt."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Alaa AbdAllah"
    },
    {
      "affs": [
        1
      ],
      "name": "wafaa mohamed"
    },
    {
      "affs": [
        2
      ],
      "name": "Amani Saber"
    },
    {
      "affs": [
        3
      ],
      "name": "Nada Sholkamy"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4rkh0m2q8n767.bib",
  "cited_by": 0,
  "doi": "10.21608/mjmr.2026.533694.2395",
  "fulltext_url": "https://mjmr.journals.ekb.eg/article_534934.html",
  "id": "4rkh0m2q8n767",
  "issns": [
    "2682-4558"
  ],
  "landing_url": "https://doi.org/10.21608/mjmr.2026.533694.2395",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "3108|Advanced Radiotherapy Techniques"
    ]
  ],
  "openalex": "W7222874488",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-25",
  "publisher": "Minia University, Faculty of Medicine",
  "ris": "https://research.draconitic.com/paper/4rkh0m2q8n767.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:15Z",
      "native_id": "d39cbdecf0c849b6b7071d0655c9cdd0",
      "source": "doaj",
      "url": "https://doi.org/10.21608/mjmr.2026.533694.2395"
    }
  ],
  "subjects": [
    {
      "field": "physics",
      "origin": "openalex:3108|Advanced Radiotherapy Techniques",
      "subfield": "applied-instrumentation"
    }
  ],
  "title": "Dosimetric Comparison of Intensity-Modulated Radiotherapy and Four-Field Three-Dimensional Conformal Radiotherapy in the Management of Prostate Cancer: A Retrospective Dual-Centre Analysis",
  "title_text": "Dosimetric Comparison of Intensity-Modulated Radiotherapy and Four-Field Three-Dimensional Conformal Radiotherapy in the Management of Prostate Cancer: A Retrospective Dual-Centre Analysis",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:15Z",
  "url": "https://research.draconitic.com/paper/4rkh0m2q8n767",
  "venue": "Minia Journal of Medical Research",
  "versions": []
}