{
  "abstract": "Introduction\n\nHolmium laser enucleation of the prostate (HoLEP) is a well-established surgical technique for benign prostatic obstruction. Although functional outcomes have been widely reported, data on sexual function during the learning phase remain limited. The aim of this study was to describe longitudinal erectile and ejaculatory outcomes during the initial learning curve of HoLEP.Material and methods\n\nThe first 254 consecutive patients undergoing HoLEP by a single surgeon were prospectively collected and retrospectively analyzed. Erectile function was evaluated using the Sexual Health Inventory for Men (SHIM) preoperatively and at 1, 3, 6, and 12 months. Ejaculatory function was assessed at the same intervals. Descriptive and comparative statistics were used, and patients were stratified into case groups to explore surgical experience impact.Results\n\nA total of 254 patients were included. Mean patient age was 70.1 ±7.7 years and mean prostate volume was 90.9 ±34.4 cc. Preoperative SHIM scores were available for 222 patients, with a median of 12.7 [5.0-20.0]. SHIM decreased at 1 month (9 [3-15]) and recovered at 3 (12 [5-20]) and 6 months (13 [6-22]). At 12 months, erectile function remained stable (12 [5-20]) with no clinically relevant deterioration. Anejaculation was observed in 93.2% at 1 month and persisted throughout follow-up (>94%), with no significant differences across case groups.Conclusions\n\nIn this real-world HoLEP series, erectile function was preserved at mid-term follow-up, with a high and persistent rate of anejaculation. Sexual outcomes did not appear influenced by surgical experience.",
  "abstract_shown": true,
  "affiliations": [
    "Hospital Clínico San Carlos, Servicio de Urología, Madrid, Spain.",
    "Instituto de Urología de la Peña-Hidalgo-Alonso, Madrid, Spain.",
    "Medical University of Graz, Department of Urology, Graz, Austria.",
    "Instituto de Investigación Sanitaria, Hospital Clínico San Carlos, Madrid, Spain.",
    "Universidad Complutense de Madrid, Spain.",
    "Unidad de Apoyo Metodológico a la Investigación, Hospital Clínico San Carlos, IdISSC, Madrid, Spain.",
    "Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.",
    "Hospital Universitario de Guadalajara, Guadalajara, Spain.",
    "Hospital Regional Universitario de Málaga, Málaga, Spain.",
    "Clínica Universidad de Navarra, Servicio de Urología, Madrid, Spain."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Luis E Ortega Polledo"
    },
    {
      "affs": [
        2
      ],
      "name": "Sascha Ahyai"
    },
    {
      "affs": [
        0,
        3,
        4
      ],
      "name": "Gómez Juan Rivas"
    },
    {
      "affs": [
        0,
        3,
        4
      ],
      "name": "Enrique Redondo González"
    },
    {
      "affs": [
        5
      ],
      "name": "Irene Serrano García"
    },
    {
      "affs": [
        1,
        6
      ],
      "name": "Geo F J Bianchini Hernández"
    },
    {
      "affs": [
        1,
        7
      ],
      "name": "Juan Carballo da Silva"
    },
    {
      "affs": [
        8
      ],
      "name": "Rodrigo España Navarro"
    },
    {
      "affs": [
        0,
        3,
        4
      ],
      "name": "Isabel Galante Romo"
    },
    {
      "affs": [
        9
      ],
      "name": "Bernardino Miñana López"
    },
    {
      "affs": [
        1
      ],
      "name": "Sergio Alonso Y Gregorio"
    },
    {
      "affs": [
        0,
        3,
        4
      ],
      "name": "Jesús Moreno Sierra"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4x4pyedx4kqen.bib",
  "cited_by": 0,
  "doi": "10.5173/ceju.2026.0061",
  "fulltext_url": "https://europepmc.org/articles/PMC13681936",
  "id": "4x4pyedx4kqen",
  "issns": [
    "2080-4806",
    "2080-4873"
  ],
  "landing_url": "https://europepmc.org/article/MED/42904096",
  "language": "eng",
  "licence": "CC-BY-NC-SA",
  "licence_label": "CC BY-NC-SA",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2748|Urinary Bladder and Prostate Research"
    ]
  ],
  "openalex": "W7204863986",
  "pdf_url": "https://europepmc.org/articles/PMC13681936?pdf=render",
  "pmcid": "PMC13681936",
  "pmid": "42904096",
  "published": "2026-07-18",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4x4pyedx4kqen.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:59Z",
      "native_id": "MED:42904096",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42904096"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2748|Urinary Bladder and Prostate Research",
      "subfield": "general"
    }
  ],
  "title": "Erectile and ejaculatory outcomes after HoLEP: A longitudinal analysis during the learning curve.",
  "title_text": "Erectile and ejaculatory outcomes after HoLEP: A longitudinal analysis during the learning curve.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:59Z",
  "url": "https://research.draconitic.com/paper/4x4pyedx4kqen",
  "venue": "Central European journal of urology",
  "versions": []
}