{
  "abstract": "Background\n\nThe right ventricular contractile pattern is altered after heart transplantation (HT). This study aims to use three-dimensional echocardiography (3DE) to comprehensively assess right ventricular contractile pattern in HT patients.Methods\n\nIn a cohort of 200 adult HT recipients, we serially assessed 3DE RV contraction patterns-including global (RVEF), longitudinal (LEF), radial (REF), and anteroposterior (AEF) ejection fractions-from the early post-operative period to 3 years. 50 HT patients were compared to matched healthy controls and open-heart surgery patients. Sex-specific reference values were derived.Results\n\nRV function parameters improved within the first year (all P < 0.05), then stabilized. At 1 year, HT recipients exhibited a distinct 3D contraction pattern compared to controls: attenuated longitudinal and anteroposterior function (LEF: 18.2% vs. 28.6%; AEF: 23.8% vs. 25.4%; P < 0.05) with compensatory enhanced radial contraction (REF: 29.8% vs. 24.6%; P < 0.05). Established reference ranges confirmed this phenotype. Cardiopulmonary bypass time were key determinants of this pattern.Conclusions\n\nHT recipients develop a unique, stabilized RV contraction pattern by one year, characterized by a shift from longitudinal to radial dominance.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.",
    "Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, Hubei, China.",
    "Hubei Province Key Laboratory of Molecular Imaging, Wuhan, Hubei, China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yuji Xie"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Wei Sun"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Linyue Zhang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yanting Zhang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Shuangshuang Zhu"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yun Yang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Xin Zhang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Sushan Xiao"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Liqiong Shi"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Qing Lv"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yuman Li"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Chun Wu"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Li Zhang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Mingxing Xie"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4xjraxew88v9b.bib",
  "cited_by": 0,
  "doi": "10.3389/fcvm.2026.1885027",
  "fulltext_url": "https://europepmc.org/articles/PMC13640019",
  "id": "4xjraxew88v9b",
  "issns": [
    "2297-055X"
  ],
  "landing_url": "https://europepmc.org/article/MED/42840949",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2705|Cardiovascular Function and Risk Factors"
    ]
  ],
  "openalex": "W7212286152",
  "pdf_url": "https://europepmc.org/articles/PMC13640019?pdf=render",
  "pmcid": "PMC13640019",
  "pmid": "42840949",
  "published": "2026-09-11",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4xjraxew88v9b.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:10Z",
      "native_id": "MED:42840949",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42840949"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Cardiovascular Function and Risk Factors",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Evolution of right ventricular contraction patterns of adult heart transplant recipients by three-dimensional echocardiography.",
  "title_text": "Evolution of right ventricular contraction patterns of adult heart transplant recipients by three-dimensional echocardiography.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:10Z",
  "url": "https://research.draconitic.com/paper/4xjraxew88v9b",
  "venue": "Frontiers in cardiovascular medicine",
  "versions": []
}