{
  "abstract": "Small bowel neuroendocrine tumors (NETs) rarely present as obscure overt gastrointestinal bleeding (OGIB), causing significant diagnostic challenges. We report a 56-year-old man who presented with OGIB that required approximately 50 units of packed red blood cells during a 6-week hospitalization. Multimodal evaluation, including computed tomography angiography, tagged red blood cell scan, video capsule endoscopy, computed tomography enterography, provocative mesenteric angiography, balloon enteroscopy, and octreotide scan, failed to identify a source. Exploratory laparotomy identified 3 mid-ileal nodules with histopathology revealing well-differentiated grade 1 neuroendocrine tumors. Bleeding resolved following resection. This case highlights the diagnostic and therapeutic role of surgical exploration in refractory OGIB.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Medicine, Henry Ford Hospital, Detroit, MI.",
    "Division of Gastroenterology and Hepatology, Henry Ford Health, Detroit, MI."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "James Mo",
      "orcid": "0009-0007-1671-4066"
    },
    {
      "affs": [
        1
      ],
      "name": "Suraj Suresh"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4xydy43mrgtpj.bib",
  "cited_by": 0,
  "doi": "10.14309/crj.0000000000002326",
  "fulltext_url": "https://europepmc.org/articles/PMC13686739",
  "id": "4xydy43mrgtpj",
  "issns": [
    "2326-3253"
  ],
  "landing_url": "https://europepmc.org/article/MED/42910086",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2715|Gastrointestinal Bleeding Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7223113064",
  "pdf_url": "https://europepmc.org/articles/PMC13686739?pdf=render",
  "pmcid": "PMC13686739",
  "pmid": "42910086",
  "published": "2026-10-21",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4xydy43mrgtpj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:10Z",
      "native_id": "MED:42910086",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42910086"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2715|Gastrointestinal Bleeding Diagnosis and Treatment",
      "subfield": "general"
    }
  ],
  "title": "When Every Test Fails: Multifocal Grade 1 Ileal Neuroendocrine Tumors Causing Transfusion-Dependent Obscure Overt Gastrointestinal Bleeding.",
  "title_text": "When Every Test Fails: Multifocal Grade 1 Ileal Neuroendocrine Tumors Causing Transfusion-Dependent Obscure Overt Gastrointestinal Bleeding.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:10Z",
  "url": "https://research.draconitic.com/paper/4xydy43mrgtpj",
  "venue": "ACG case reports journal",
  "versions": []
}