{
  "abstract": "Familial Mediterranean fever (FMF) rarely presents without a periodic fever. We report the case of a 16-year-old girl who developed recurrent abdominal pain after coronavirus disease 2019 without fever. The initial evaluation, including endoscopy, was unremarkable, except for mildly elevated fecal calprotectin (182.1 μg/g). On readmission, peritoneal signs, mild pleural effusion, and elevated serum amyloid A (113.9 mg/L) were noted, while the C-reactive protein level remained normal. Colchicine promptly suppressed these attacks. MEFV sequencing revealed a homozygous E148Q mutation, supporting an atypical FMF. Fecal calprotectin and serum amyloid A levels normalized within one month. This case underscores the importance of FMF in post-infectious recurrent abdominal pain and highlights targeted biomarkers and genetics for making a timely diagnosis.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 17,
  "authors": [
    {
      "name": "Nobuhiro Ueno"
    },
    {
      "name": "Hiromichi Sugai"
    },
    {
      "name": "Suzumi Ujiie"
    },
    {
      "name": "Ryunosuke Hayashi"
    },
    {
      "name": "Kazuki Dai"
    },
    {
      "name": "Manami Hayashi"
    },
    {
      "name": "Yu Kobayashi"
    },
    {
      "name": "Yuki Murakami"
    },
    {
      "name": "Aki Sakatani"
    },
    {
      "name": "Keitaro Takahashi"
    },
    {
      "name": "Tatsuya Dokoshi"
    },
    {
      "name": "Katsuyoshi Ando"
    },
    {
      "name": "Shin Kashima"
    },
    {
      "name": "Kentaro Moriichi"
    },
    {
      "name": "Hiroki Tanabe"
    },
    {
      "name": "Mishie Tanino"
    },
    {
      "name": "Mikihiro Fujiya"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4xzqxwr2jgh39.bib",
  "cited_by": 0,
  "doi": "10.2169/internalmedicine.6541-25",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6541-25/_article",
  "id": "4xzqxwr2jgh39",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6541-25/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "1312|Inflammasome and immune disorders"
    ]
  ],
  "openalex": "W7129072185",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_6541-25/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-15",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4xzqxwr2jgh39.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.6541-25",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/65/18/65_6541-25/_article"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Inflammasome and immune disorders",
      "subfield": "molecular-biology"
    }
  ],
  "title": "Familial Mediterranean Fever Presenting with Recurrent Abdominal Pain without Periodic Fever Following COVID-19",
  "title_text": "Familial Mediterranean Fever Presenting with Recurrent Abdominal Pain without Periodic Fever Following COVID-19",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/4xzqxwr2jgh39",
  "venue": "Internal Medicine",
  "versions": []
}