{
  "abstract": "The preparation of a series of enantioenriched α‐substituted primary amines using rhodium‐catalyzed asymmetric transfer hydrogenation of ortho‐hydroxyaryl N─H imines is reported. The reaction proceeds under mild conditions using a low catalyst loading and ammonium formate as the hydrogen source, delivering the reduced compounds in high yields (up to 99%) and enantioselectivities (up to 99% ee).",
  "abstract_shown": true,
  "affiliations": [
    "Institute of Chemistry for Life and Health Sciences CNRS, CSB2D Team Paris France",
    "Faculty of Pharmaceutical Sciences Shenzhen University of Advanced Technology Shenzhen Guangdong China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Chonghuo Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Guillaume Lefèvre",
      "orcid": "0000-0001-9409-5861"
    },
    {
      "affs": [
        1
      ],
      "name": "Qin Yin",
      "orcid": "0000-0003-3534-3786"
    },
    {
      "affs": [
        0
      ],
      "name": "Phannarath Phansavath"
    },
    {
      "affs": [
        0
      ],
      "name": "Virginie Ratovelomanana‐Vidal",
      "orcid": "0000-0003-1167-1195"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4yaamz7f8xsgj.bib",
  "cited_by": 1,
  "doi": "10.1002/chem.71466",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13715052/",
  "id": "4yaamz7f8xsgj",
  "issns": [
    "0947-6539",
    "1521-3765"
  ],
  "landing_url": "https://doi.org/10.1002/chem.71466",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research Article"
    ],
    [
      "openalex",
      "1604|Asymmetric Hydrogenation and Catalysis"
    ]
  ],
  "openalex": "W7170854918",
  "pdf_url": null,
  "pmcid": "PMC13715052",
  "pmid": "42498498",
  "published": "2026-07-24",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/4yaamz7f8xsgj.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T12:22:26Z",
      "native_id": "PMC13715052",
      "source": "pmc",
      "url": "https://doi.org/10.1002/chem.71466"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1604|Asymmetric Hydrogenation and Catalysis",
      "subfield": "inorganic"
    }
  ],
  "title": "Rhodium‐Catalyzed Synthesis of Enantioenriched α‐Substituted Primary Amines Through Asymmetric Transfer Hydrogenation",
  "title_text": "Rhodium‐Catalyzed Synthesis of Enantioenriched α‐Substituted Primary Amines Through Asymmetric Transfer Hydrogenation",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:22:26Z",
  "url": "https://research.draconitic.com/paper/4yaamz7f8xsgj",
  "venue": "Chemistry (Weinheim an Der Bergstrasse, Germany)",
  "versions": []
}