{
  "abstract": "The FDA’s real-time clinical trial initiative marks a pivotal shift in regulating clinical trials, yet accelerating data flows may outpace the governance, statistical safeguards, and inclusive infrastructure required for trustworthy evidence. To address these issues, the commentary identifies four key challenges and proposes a three-pillar governance framework to ensure rigorous, equitable, and continuously adaptive oversight and operations.",
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  "affiliations": [],
  "article_type": "brief report",
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "name": "Azizi A. Seixas",
      "orcid": "0000-0003-0843-2679"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/4yq8rwpw5cx9v.bib",
  "cited_by": 0,
  "doi": "10.1038/s43856-026-01909-8",
  "fulltext_url": "https://europepmc.org/articles/PMC13720012",
  "id": "4yq8rwpw5cx9v",
  "issns": [
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  "language": "eng",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
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  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Comment"
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  "pdf_url": "https://www.nature.com/articles/s43856-026-01909-8.pdf",
  "pmcid": "PMC13720012",
  "pmid": "42957779",
  "published": "2026-10-28",
  "publisher": "Springer Science and Business Media LLC",
  "ris": "https://research.draconitic.com/paper/4yq8rwpw5cx9v.ris",
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      "url": "https://doi.org/10.1038/s43856-026-01909-8"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "issn:2730-664X",
      "subfield": "general"
    }
  ],
  "title": "Governing accelerated evidence in real-time clinical trials",
  "title_text": "Governing accelerated evidence in real-time clinical trials",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:21:00Z",
  "url": "https://research.draconitic.com/paper/4yq8rwpw5cx9v",
  "venue": "Communications Medicine",
  "versions": []
}