{
  "abstract": "This single-center retrospective cohort study included infertile patients treated between October 2019 and December 2024, comparing an endometriosis (EMS) cohort (n = 250, laparoscopically and histopathologically confirmed) with a control cohort (n = 750, tubal-factor infertility only, EMS excluded by laparoscopy). All patients underwent laparoscopy, hysteroscopy, and endometrial biopsy; chronic endometritis (CE) was diagnosed by cluster of differentiation 38/cluster of differentiation 138 immunohistochemistry, and EMS was staged by revised American Society for Reproductive Medicine. CE detection rate was significantly higher in the EMS cohort than in controls (P < .001). Within the EMS cohort, CE prevalence was 45.1% in moderate-to-severe (stage III–IV) disease versus 24.0% in mild (stage I–II) disease (P = .001). Factors independently associated with concurrent CE were moderate-to-severe EMS, repeated intrauterine procedures, infertility duration ≥ 3 years, chronic pelvic pain, and higher gravidity (all P < .05). At 1 year, the EMS cohort had a lower clinical pregnancy rate (70.0% vs 80.0%), higher persistent infertility rate (30.0% vs 20.0%), and higher early pregnancy loss rate (16.0% vs 9.2%) than controls (all P < .05). Within the EMS cohort, concurrent CE was associated with a lower clinical pregnancy rate (56.0% vs 76.0%), higher persistent infertility rate (44.0% vs 24.0%), and higher early pregnancy loss rate (31.0% vs 11.3%) than EMS alone (all P = .002). These findings demonstrate a significant cross-sectional association between EMS and CE, with higher CE detection in advanced-stage EMS; however, causality and temporal sequence cannot be determined, reproductive outcomes were exploratory and unadjusted, and this single-center retrospective dataset is insufficient to support universal diagnostic or therapeutic guidelines.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Gynaecology, Guangzhou Women and Children’s Medical Center Liuzhou Hospital, Liuzhou, Guangxi, China",
    "Guangxi Clinical Research Center for Obstetrics and Gynecology, Liuzhou, Guangxi, China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "HuiLiu Fan",
      "orcid": "0009-0009-2111-6778"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Bei Liu"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "XiaoXia Wu"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "HongLan Wei"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/52emz7w9aafne.bib",
  "cited_by": 0,
  "doi": "10.1097/md.0000000000051450",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727181/?tool=EBI",
  "id": "52emz7w9aafne",
  "issns": [
    "0304-5412",
    "1536-5964",
    "0025-7974"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13727181",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "5600"
    ],
    [
      "heading",
      "Observational Study"
    ],
    [
      "heading",
      "Research Article"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727181/pdf/?tool=EBI",
  "pmcid": "PMC13727181",
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Wolters Kluwer Health",
  "ris": "https://research.draconitic.com/paper/52emz7w9aafne.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T15:20:51Z",
      "native_id": "PMC:PMC13727181",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13727181"
    },
    {
      "first_seen": "2026-11-05T12:23:18Z",
      "native_id": "PMC13727181",
      "source": "pmc",
      "url": "https://doi.org/10.1097/md.0000000000051450"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:F27",
      "subfield": "general"
    }
  ],
  "title": "Correlation between endometriosis and chronic endometritis : A retrospective cohort study",
  "title_text": "Correlation between endometriosis and chronic endometritis : A retrospective cohort study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:22:54Z",
  "url": "https://research.draconitic.com/paper/52emz7w9aafne",
  "venue": "Medicine",
  "versions": []
}