{
  "abstract": "Background: Although sense of coherence (SOC) is a core concept to promote healthy aging, evidence of whether SOC improves loss of independence (LOI) or death is lacking. We aimed to investigate the association between SOC and LOI or death in older adults. Methods: We enrolled independent older adults aged 65 years or over from a population-based cohort. SOC was assessed using a three-item SOC scale at baseline. The primary outcome was a composite of LOI (defined by Japanese long-term care insurance certification) or death. We investigated the association of SOC with LOI or death using the Cox proportional hazards model. Results: During a median follow-up of 5.8 years, 128 out of 1,661 (7.7%) participants had LOI or death. Lower SOC (per 1 standard deviation [SD] decrease) was associated with a higher risk of LOI or death (adjusted hazard ratio 1.25, 95% confidence interval [CI] 1.07 to 1.46, p = 0.005). Lower SOC (per 1 SD decrease) was associated with a higher risk of death (adjusted hazard ratio 1.24, 95% CI 1.03 to 1.50, p = 0.022) as well. Conclusions: Older adults with a lower SOC were more likely to experience LOI or death. Enhancing SOC could promote healthy aging in older adults.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Healthcare Epidemiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan",
    "Department of General Internal Medicine, Hashimoto Municipal Hospital, Wakayama, Japan",
    "Section of Clinical Epidemiology, Department of Community Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan",
    "Center for Innovative Research for Communities and Clinical Excellence (CiRC2LE), Fukushima Medical University, Fukushima, Japan"
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Sho Matsushita"
    },
    {
      "affs": [
        1
      ],
      "name": "Hajime Yamazaki"
    },
    {
      "affs": [
        2
      ],
      "name": "Yoshie Yamada"
    },
    {
      "affs": [
        3
      ],
      "name": "Yusuke Ogawa"
    },
    {
      "name": "Yosuke Yamamoto"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/536rt5qzp6ga6.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pone.0355726",
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  "id": "536rt5qzp6ga6",
  "issns": [
    "1932-6203"
  ],
  "landing_url": "https://doi.org/10.1371/journal.pone.0355726",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "3600|Health, psychology, and well-being"
    ],
    [
      "plos",
      "/Biology and life sciences/Nutrition/Diet/Alcohol consumption"
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      "/Medicine and health sciences/Cardiology/Cardiovascular medicine/Cardiovascular diseases"
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      "/Medicine and health sciences/Medical conditions/Cardiovascular diseases"
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      "/Medicine and health sciences/Mental health and psychiatry"
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      "/Medicine and health sciences/Neurology/Dementia"
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    [
      "plos",
      "/Medicine and health sciences/Nutrition/Diet/Alcohol consumption"
    ],
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      "plos",
      "/Medicine and health sciences/Public and occupational health/Physical activity"
    ],
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      "plos",
      "/People and places/Population groupings/Age groups/Adults/Elderly"
    ]
  ],
  "openalex": "W7204832415",
  "pdf_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0355726&type=printable",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-31",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/536rt5qzp6ga6.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:02Z",
      "native_id": "10.1371/journal.pone.0355726",
      "source": "plos",
      "url": "https://doi.org/10.1371/journal.pone.0355726"
    }
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  "subjects": [
    {
      "field": "medicine",
      "origin": "plos:cardiovascular diseases",
      "subfield": "cardiovascular"
    },
    {
      "field": "medicine",
      "origin": "plos:epidemiology",
      "subfield": "epidemiology-public-health"
    },
    {
      "field": "medicine",
      "origin": "plos:nutrition",
      "subfield": "nutrition"
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  ],
  "title": "Association between sense of coherence and loss of independence or death in older adults: Locomotive Syndrome and Health Outcomes in Aizu Cohort Study",
  "title_text": "Association between sense of coherence and loss of independence or death in older adults: Locomotive Syndrome and Health Outcomes in Aizu Cohort Study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:02Z",
  "url": "https://research.draconitic.com/paper/536rt5qzp6ga6",
  "venue": "PLOS One",
  "versions": []
}