{
  "abstract": "The persistence of antibiotics in aquatic environments has emerged as a critical environmental challenge due to their extensive use, incomplete metabolism, and continuous release from municipal, hospital, and industrial sources. Their accumulation in water and wastewater systems fosters antimicrobial resistance, disrupts ecosystems, and poses severe risks to public health. Conventional adsorbents such as activated carbon and zeolites often fall short in terms of selectivity, regeneration, and adsorption capacity, necessitating innovative alternatives. Metal-organic frameworks (MOFs), with their tunable porosity, high surface areas, adjustable chemical functionalities, and structural diversity, have attracted significant attention as next-generation adsorbents for antibiotic removal. This review provides a comprehensive discussion of the occurrence and impacts of antibiotics in aquatic systems, followed by a critical evaluation of the adsorption performance of pristine MOFs, MOF derivatives, and MOF-based composites. Emphasis is placed on synthetic methodologies, purification/activation strategies, and mechanistic insights underlying antibiotic-MOF interactions. Furthermore, the study highlights the regeneration potential of MOFs for sustainable applications, compares their performance with conventional adsorbents, and identifies the persisting challenges in stability, scalability, and selectivity. Finally, knowledge gaps and future directions are outlined, focusing on defect engineering, hybrid frameworks, and other critical factors governing efficient application in real wastewater treatment to accelerate the translation of laboratory studies into practical deployment. By consolidating advances and challenges, this work positions MOFs as promising candidates for addressing the global threat of antibiotic pollution in water and wastewater.",
  "abstract_shown": true,
  "affiliations": [
    "Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS) Chennai Tamil Nadu India kwharyourday@gmail.com.",
    "Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology P. M. B. 4000 Ogbomoso Oyo State Nigeria osbello@lautech.edu.ng.",
    "Department of Biochemistry and Forensic Science, Abiola Ajimobi Technical University (formerly First Technical University) Ibadan Nigeria.",
    "Department of Industrial Chemistry, Abiola Ajimobi Technical University (formerly First Technical University) Ibadan Nigeria.",
    "Department of Industrial Chemistry, University of Ilesa Ilesa Osun State Nigeria.",
    "Good Health and Wellbeing Research Clusters (SDG 03), University of Ilesa Ilesa Osun State Nigeria.",
    "Department of Chemistry, Faculty of Natural and Applied Science, Lead City University Ibadan Nigeria.",
    "Department of Chemistry, University of Pretoria South Africa.",
    "Department of Chemistry, Faculty of Science, Islamic University of Madinah Madinah 42351 Saudi Arabia."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Kayode Adesina Adegoke",
      "orcid": "0000-0002-7502-0132"
    },
    {
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        2
      ],
      "name": "Cecilia Opeyemi Babarinde",
      "orcid": "0009-0008-4854-2112"
    },
    {
      "affs": [
        1
      ],
      "name": "Oyeladun Rhoda Adegoke"
    },
    {
      "affs": [
        3
      ],
      "name": "Olatunde Sunday Oladeji"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Abel Kolawole Oyebamiji",
      "orcid": "0000-0002-8932-6327"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Abayomi Bamisaye",
      "orcid": "0000-0003-1466-9058"
    },
    {
      "affs": [
        3
      ],
      "name": "Abibat Adeola Adesina"
    },
    {
      "affs": [
        1
      ],
      "name": "Olugbenga Solomon Bello",
      "orcid": "0000-0001-8732-1816"
    },
    {
      "affs": [
        8
      ],
      "name": "Musa A Said",
      "orcid": "0000-0003-3073-5449"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/560hv5jgjdqxp.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra04068c",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13717510/?tool=EBI",
  "id": "560hv5jgjdqxp",
  "issns": [
    "2046-2069"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13717510",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Chemistry"
    ],
    [
      "openalex",
      "1604|Metal-Organic Frameworks: Synthesis and Applications"
    ]
  ],
  "openalex": "W7224339659",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13717510/pdf/?tool=EBI",
  "pmcid": "PMC13717510",
  "pmid": "42959717",
  "published": "2026-10-29",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/560hv5jgjdqxp.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:37Z",
      "native_id": "PMC:PMC13717510",
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    {
      "first_seen": "2026-11-02T12:21:49Z",
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      "url": "https://doi.org/10.1039/d6ra04068c"
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  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1604|Metal-Organic Frameworks: Synthesis and Applications",
      "subfield": "inorganic"
    }
  ],
  "title": "Metal–organic frameworks for antibiotic removal from water and wastewater",
  "title_text": "Metal–organic frameworks for antibiotic removal from water and wastewater",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:21:49Z",
  "url": "https://research.draconitic.com/paper/560hv5jgjdqxp",
  "venue": "RSC advances",
  "versions": []
}