{
  "abstract": "-substitution, and molecular hybridization on inhibitory potency and selectivity. This review summarizes the most promising isatin-based cholinesterase inhibitors reported from 2020 to the present, highlighting their biological activities, structure-activity relationships, and potential for the development of next-generation anti-Alzheimer therapeutics.",
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  "article_type": null,
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  "author_total": 4,
  "authors": [
    {
      "name": "Muhammad Shahzad"
    },
    {
      "name": "Alia Mushtaq"
    },
    {
      "name": "Christophe Rochais"
    },
    {
      "name": "Muhammad Moazzam Naseer"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/57vb8abv3thnv.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra06493k",
  "fulltext_url": null,
  "id": "57vb8abv3thnv",
  "issns": [
    "2046-2069"
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  "landing_url": "https://normandie-univ.hal.science/hal-05767891v1",
  "language": "en",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
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      "hal",
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    [
      "openalex",
      "2736|Cholinesterase and Neurodegenerative Diseases"
    ]
  ],
  "openalex": "W7213543776",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-28",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/57vb8abv3thnv.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:42Z",
      "native_id": "hal-05767891",
      "source": "hal",
      "url": "https://normandie-univ.hal.science/hal-05767891v1"
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  "subjects": [
    {
      "field": "chemistry",
      "origin": "hal:1.chim.ther",
      "subfield": "medicinal"
    }
  ],
  "title": "Isatin derivatives as potent cholinesterase inhibitors: recent developments and future challenges",
  "title_text": "Isatin derivatives as potent cholinesterase inhibitors: recent developments and future challenges",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:42Z",
  "url": "https://research.draconitic.com/paper/57vb8abv3thnv",
  "venue": "RSC Advances",
  "versions": []
}