{
  "abstract": "Synthesis of hydroxyapatite (Ca₁₀(PO₄)₆(OH)₂, HAp) containing titanium (Ti) in the tetravalent state in its channel was successfully demonstrated by employing a post-treatment involving impregnation with a metal alkoxide followed by heat treatment, together with Rietveld refinement. Infrared spectroscopic analyses suggested that the excess positive charge arising from the cation incorporation was compensated for by proton dissociation from hydroxide ions located in the channel, resulting in the formation of titanium oxo groups in the channel. The incorporation of Ti ions into the interstitial site located in the channel resulted in light absorption characteristics distinct from those typically observed for isomorphous substitution, suggesting broadening of the potential properties of HAp-based materials owing to the expansion of their compositional and structural diversity.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Materials Science, Graduate School of Engineering Science, Akita University 1-1 Tegatagakuen-machi Akita-shi Akita 010-8502 Japan saitok@gipc.akita-u.ac.jp katos@gipc.akita-u.ac.jp.",
    "Kagami Memorial Research Institute for Materials Science and Technology, Waseda University 2-8-26 Nishiwaseda Shinjuku-ku Tokyo 169-0054 Japan."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Xiao Chen"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Kanji Saito",
      "orcid": "0000-0001-5951-0097"
    },
    {
      "affs": [
        0
      ],
      "name": "Masataka Ogasawara"
    },
    {
      "affs": [
        0
      ],
      "name": "Sumio Kato"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5882d9f333mcw.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra08560a",
  "fulltext_url": "https://europepmc.org/articles/PMC13702838",
  "id": "5882d9f333mcw",
  "issns": [
    "2046-2069"
  ],
  "landing_url": "https://europepmc.org/article/MED/42936294",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2204|Bone Tissue Engineering Materials"
    ]
  ],
  "openalex": "W7223653796",
  "pdf_url": "https://europepmc.org/articles/PMC13702838?pdf=render",
  "pmcid": "PMC13702838",
  "pmid": "42936294",
  "published": "2026-10-26",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5882d9f333mcw.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:22:12Z",
      "native_id": "MED:42936294",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42936294"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:2046-2069",
      "subfield": "general"
    }
  ],
  "title": "Incorporation of Ti⁴⁺ into the channel of hydroxyapatite by loading of Ti and post-calcination.",
  "title_text": "Incorporation of Ti⁴⁺ into the channel of hydroxyapatite by loading of Ti and post-calcination.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:22:12Z",
  "url": "https://research.draconitic.com/paper/5882d9f333mcw",
  "venue": "RSC advances",
  "versions": []
}