{
  "abstract": "Background:: To compare the incidence of stroke at 1 and 2 years following transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR), aiming to inform clinical decision-making regarding the safety and effectiveness of these interventions.\n\nMethods:: A random-effects meta-analysis was conducted including 9 randomized controlled trials (RCTs) with a total of 9865 patients. The primary endpoint was the incidence of stroke at 1 and 2 years post-procedure.\n\nResults:: At 1 year, TAVR was associated with a lower incidence of stroke compared with SAVR (odds ratio (OR), 0.77; 95% confidence interval (CI), 0.61–0.98; p = 0.03). No significant difference was observed at 2 years (OR, 0.87; 95% CI, 0.65–1.17; p = 0.37).\n\nConclusions:: TAVR significantly reduces the risk of stroke within 1 year post-procedure compared with SAVR; however, this effect was not maintained at 2 years. These findings highlight the early benefit of TAVR, while the long-term advantage requires further investigation.\n\nThe PROSPERO Registration:: This study has been registered with PROSPERO, registration number: CRD42025636191, https://www.crd.york.ac.uk/PROSPERO/view/CRD42025636191.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Cardiology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, 330031 Nanchang, Jiangxi, China",
    "Jiangxi Hypertension Research Institute, 330006 Nanchang, Jiangxi, China",
    "Jiangxi Medical College, Nanchang University, 330031 Nanchang, Jiangxi, China"
  ],
  "article_type": "systematic review",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Haochen Liu",
      "orcid": "0009-0001-1079-2940"
    },
    {
      "affs": [
        2
      ],
      "name": "Zhidan Xiao"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Jiahao Zou"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Xiaoping Peng",
      "orcid": "0000-0003-4766-3963"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/59ay1g4j61ytj.bib",
  "cited_by": 0,
  "doi": "10.31083/rcm49672",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13732676/",
  "id": "59ay1g4j61ytj",
  "issns": [
    "1530-6550",
    "2153-8174"
  ],
  "landing_url": "https://doi.org/10.31083/rcm49672",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Systematic Review"
    ],
    [
      "openalex",
      "2705|Cardiac Valve Diseases and Treatments"
    ]
  ],
  "openalex": "W7225235751",
  "pdf_url": "https://storage.imrpress.com/IMR/2105098523012554800/application/2153-8174-27-10-49672.pdf",
  "pmcid": "PMC13732676",
  "pmid": "42985463",
  "published": "2026-09-30",
  "publisher": "IMR Press",
  "ris": "https://research.draconitic.com/paper/59ay1g4j61ytj.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:22:37Z",
      "native_id": "PMC13732676",
      "source": "pmc",
      "url": "https://doi.org/10.31083/rcm49672"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Cardiac Valve Diseases and Treatments",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Risk of Short-Term Stroke in Non-High-Risk Patients Undergoing Transcatheter Aortic Valve Replacement vs Surgical Aortic Valve Replacement: A Systematic Review and Meta-Analysis",
  "title_text": "Risk of Short-Term Stroke in Non-High-Risk Patients Undergoing Transcatheter Aortic Valve Replacement vs Surgical Aortic Valve Replacement: A Systematic Review and Meta-Analysis",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:22:37Z",
  "url": "https://research.draconitic.com/paper/59ay1g4j61ytj",
  "venue": "Reviews in Cardiovascular Medicine",
  "versions": []
}