{
  "abstract": "Background\n\nAcinetobacter baumannii is a major nosocomial pathogen because of its genomic plasticity and capacity to acquire multidrug resistance (MDR), particularly resistance to carbapenems. The World Health Organization classifies carbapenem-resistant A. baumannii as a critical-priority pathogen. Molecular epidemiological data from Latin America remain limited, especially for northern Peru.Methods\n\nDrug-resistant A. baumannii isolates collected between 2015 and 2021 at a tertiary referral hospital in northern Peru were characterized by antimicrobial susceptibility testing, BOX-PCR, ERIC-PCR, REP-PCR, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).Results\n\nAll seven isolates met the criteria for MDR, and Ac-4268 showed an extensively drug-resistant phenotype. Repetitive-element PCR identified a group of six isolates with similar banding profiles and a divergent isolate, Ac-4268. Several isolates in the six-isolate group retained susceptibility to one or more aminoglycosides, whereas Ac-4268 was resistant to all antimicrobials tested. The combined molecular and phenotypic findings are consistent with the possible persistence of a dominant related lineage, but they do not establish transmission without whole-genome sequencing and epidemiological linkage data.Conclusion\n\nThis study provides additional molecular epidemiological evidence on MDR A. baumannii in northern Peru. The findings suggest that a dominant related lineage may have persisted in the hospital alongside a genetically divergent isolate with an extensively drug-resistant phenotype. Confirmation of clonal transmission requires higher-resolution genomic and epidemiological analyses.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Biotechnology, Center for Research and Innovation in Multidisciplinary Active Sciences (CIICAM), Lambayeque, Peru.",
    "Division of Microbial Resources of Chemical, Biological and Agricultural Pluridisciplinary Research Center (CPQBA), University of Campinas, Sao Paulo, Brazil.",
    "School of Medical Sciences, University of Campinas, Campinas, Sao Paulo, Brazil.",
    "Bioengineering Section, Department of Engineering, Pontificia Universidad Católica del Perú, San Miguel, Lima, Peru.",
    "Instituto de Ciencias Ómicas y Biotecnología Aplicada, Pontificia Universidad Católica del Perú, San Miguel, Lima, Peru."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Kevin G Quispe Choque"
    },
    {
      "affs": [
        0
      ],
      "name": "Nataly Ruiz Quiñones"
    },
    {
      "affs": [
        1
      ],
      "name": "Milena Binatti Ferreira"
    },
    {
      "affs": [
        1
      ],
      "name": "Ana L Perini-Leme-Giordano",
      "orcid": "0000-0002-9584-434X"
    },
    {
      "affs": [
        2
      ],
      "name": "Angélica Zaninelli Schreiber"
    },
    {
      "affs": [
        1
      ],
      "name": "Fabiana Fantinatti Garboggini"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Fanny L Casado"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Rene Flores Clavo"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5axfcpv6y34v7.bib",
  "cited_by": 0,
  "doi": "10.1016/j.nmni.2026.101864",
  "fulltext_url": "https://europepmc.org/articles/PMC13694419",
  "id": "5axfcpv6y34v7",
  "issns": [
    "2052-2975"
  ],
  "landing_url": "https://europepmc.org/article/MED/42926754",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1313|Antibiotic Resistance in Bacteria"
    ]
  ],
  "openalex": "W7221318799",
  "pdf_url": "https://europepmc.org/articles/PMC13694419?pdf=render",
  "pmcid": "PMC13694419",
  "pmid": "42926754",
  "published": "2026-10-10",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5axfcpv6y34v7.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:18Z",
      "native_id": "MED:42926754",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42926754"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:1313|Antibiotic Resistance in Bacteria",
      "subfield": "general"
    }
  ],
  "title": "Molecular evidence of a dominant multidrug resistant Acinetobacter baumannii lineage in a tertiary hospital in northern Peru.",
  "title_text": "Molecular evidence of a dominant multidrug resistant Acinetobacter baumannii lineage in a tertiary hospital in northern Peru.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:18Z",
  "url": "https://research.draconitic.com/paper/5axfcpv6y34v7",
  "venue": "New microbes and new infections",
  "versions": []
}