{
  "abstract": "Introduction: Hyalinizing Trabecular Tumor (HTT) is an extremely rare thyroid neoplasm. Preoperative imaging diagnosis and Fine-Needle Aspiration Cytology (FNAC) are considerably challenging. We present a case of invasive HTT, describing its clinical course and imaging manifestations.\n\nCase Description: A 49-year-old woman presented with a 12cm left thyroid mass that had been incidentally detected as a 9×8mm nodule ten years previously. Following asymptomatic gradual enlargement, she developed severe dyspnea in March 2024, prompting admission. Physical examination confirmed a large, firm left thyroid mass. Ultrasound (US) was limited by the lesion's size. Dual-Phase Contrast-Enhanced CT (DP-CECT) revealed a 12cm oval mass replacing the left lobe. US-FNAC yielded suspicious for malignancy (TBSRTC Category III). She underwent left thyroid lobectomy and isthmusectomy. Pathology and immunohistochemistry confirmed HTT with focal capsular invasion. The patient recovered uneventfully during follow-up.\n\nConclusion: Elucidating the characteristic features of HTT will facilitate early diagnosis and clinical intervention, providing valuable insights for future clinical research.",
  "abstract_shown": true,
  "affiliations": [
    "Academy of Medical Imaging, Guizhou Medical University, Guiyang, Guizhou 550004, China",
    "Department of Radiology, Luzhou People's Hospital, Luzhou 646000, China",
    "Department of Pathology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China",
    "Department of Ultrasound Center, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, China"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Caihong Wang",
      "orcid": "0009-0003-3364-2827"
    },
    {
      "affs": [
        1
      ],
      "name": "Fei Wang"
    },
    {
      "affs": [
        0
      ],
      "name": "Dan Qin"
    },
    {
      "affs": [
        0
      ],
      "name": "Yuyu Hua"
    },
    {
      "affs": [
        0
      ],
      "name": "Ying Yang"
    },
    {
      "affs": [
        2
      ],
      "name": "Yining Xiang"
    },
    {
      "affs": [
        3
      ],
      "name": "Jing Wen"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5by3kzy9jva4s.bib",
  "cited_by": 0,
  "doi": "10.2174/0115734056452029260623060307",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13728980/",
  "id": "5by3kzy9jva4s",
  "issns": [
    "1573-4056"
  ],
  "landing_url": "https://doi.org/10.2174/0115734056452029260623060307",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Medicine, Imaging, Radiology, Nuclear Medicine"
    ],
    [
      "openalex",
      "2712|Thyroid Cancer Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7170738503",
  "pdf_url": null,
  "pmcid": "PMC13728980",
  "pmid": "42515923",
  "published": "2026-07-22",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5by3kzy9jva4s.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:21:49Z",
      "native_id": "PMC13728980",
      "source": "pmc",
      "url": "https://doi.org/10.2174/0115734056452029260623060307"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2712|Thyroid Cancer Diagnosis and Treatment",
      "subfield": "endocrinology-metabolism"
    }
  ],
  "title": "Giant Hyalinizing Trabecular Tumor of the Thyroid: A Case Report and Literature Review",
  "title_text": "Giant Hyalinizing Trabecular Tumor of the Thyroid: A Case Report and Literature Review",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:21:49Z",
  "url": "https://research.draconitic.com/paper/5by3kzy9jva4s",
  "venue": "Current Medical Imaging",
  "versions": []
}