{
  "abstract": "Traumatic brain injury (TBI) is the leading cause of death and disability in people under 40 worldwide. There is an unmet need for detection and treatment of life-threatening TBI when computed tomography (CT) scanners and neurosurgeons are unavailable. We developed a new handheld frequency-domain multidetector infrared hemorrhage detection device. Using the new device, military pre-hospital medics required <4 minutes to detect life-threatening subdural hematoma in a sheep model. We developed a second device that allows non-neurosurgeons to safely create a burr hole and partially remove clotted subdural blood. In sheep, the treatment device reduced intracranial pressure within 20 minutes, and improved post-anesthesia blinded neurological outcomes. With human use adaptation, these devices could allow rapid detection and initial treatment of some life-threatening TBIs in challenging situations.",
  "abstract_shown": true,
  "affiliations": [
    "Uniformed Services University of the Health Sciences"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 21,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "D. L. Brody"
    },
    {
      "name": "B. A. Dengler"
    },
    {
      "name": "J. P. Angelo"
    },
    {
      "name": "D. W. Blodgett"
    },
    {
      "name": "A. B. Cohen"
    },
    {
      "name": "D. G. Drewry"
    },
    {
      "name": "M. J. Fitch"
    },
    {
      "name": "N. Goonasekeram"
    },
    {
      "name": "A. J. Januszkiewicz"
    },
    {
      "name": "T. Knapp"
    },
    {
      "name": "B. Kohler"
    },
    {
      "name": "J. Mark"
    },
    {
      "name": "I. S. McAdams"
    },
    {
      "name": "K. M. Perrino"
    },
    {
      "name": "C. L. Rodriguez"
    },
    {
      "name": "T. A. Sleasman"
    },
    {
      "name": "G. L. Spicer"
    },
    {
      "name": "N. E. Steiner"
    },
    {
      "name": "A. P. Vieth"
    },
    {
      "name": "J. J. Wathen"
    },
    {
      "name": "K. C. Wolfe"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5c71m3n16jf8d.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.11.03.763711",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.11.03.763711v1.full",
  "id": "5c71m3n16jf8d",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.11.03.763711v1",
  "language": null,
  "licence": "CC0-1.0",
  "licence_label": "CC0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/publicdomain/zero/1.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "neuroscience"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.11.03.763711v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-03",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5c71m3n16jf8d.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:21:05Z",
      "native_id": "10.64898/2026.11.03.763711",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.11.03.763711v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:neuroscience",
      "subfield": "neuroscience"
    }
  ],
  "title": "Rapid Detection and Initial Treatment of Life-Threatening Subdural Hematoma in a Sheep Model",
  "title_text": "Rapid Detection and Initial Treatment of Life-Threatening Subdural Hematoma in a Sheep Model",
  "type": "preprint",
  "updated_at": "2026-11-06T00:20:51Z",
  "url": "https://research.draconitic.com/paper/5c71m3n16jf8d",
  "venue": "bioRxiv",
  "versions": []
}