{
  "abstract": "Precise quantitative and spatial control of plant gene expression is typically attributed to cis-regulatory elements in promoters and other non-coding sequences. The extent to which exon-encoded regulatory information shapes plant gene expression and how remains unclear. Here we used BRASSINOSTEROID INSENSITIVE 1 (BRI1) as a model locus and found that it contains an exonic enhancer (EE), which is essential to establish the spatial BRI1 expression pattern. Its disruption restricts BRI1 expression and impairs BRI1-dependent root growth, linking exon-encoded regulatory information and development. The BRI1 EE acts in concert with its promoter, and related receptor kinase genes likewise harbor regulatory information within their coding sequences. Genome-wide surveys show that candidate EEs are associated with highly connected chromatin interaction networks and transcriptionally active loci. Moreover, species comparisons suggest that common features of exon-encoded regulatory information extend across diverse plant lineages. Thus, exon-encoded regulatory information is a vital component of plant gene regulation.",
  "abstract_shown": true,
  "affiliations": [
    "University of Lausanne"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "name": "R. Denia-Mondejar"
    },
    {
      "name": "P. Brunot-Garau"
    },
    {
      "name": "X. Ma"
    },
    {
      "name": "A. Serrano-Mislata"
    },
    {
      "name": "M. Dolores Gomez"
    },
    {
      "name": "D. Latrasse"
    },
    {
      "name": "M. Benhamed"
    },
    {
      "affs": [
        0
      ],
      "name": "C. S. Hardtke"
    },
    {
      "name": "N. Blanco-Tourinan"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5d4mwds3q35nv.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.21.753065",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.09.21.753065v1.full",
  "id": "5d4mwds3q35nv",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.09.21.753065v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "plant biology"
    ],
    [
      "openalex",
      "1110|Plant Molecular Biology Research"
    ]
  ],
  "openalex": "W7214123724",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.09.21.753065v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-21",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5d4mwds3q35nv.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:24:08Z",
      "native_id": "10.64898/2026.09.21.753065",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.09.21.753065v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:plant biology",
      "subfield": "plant-biology"
    }
  ],
  "title": "Brassinosteroid receptors reveal conserved features of exon-embedded gene regulation",
  "title_text": "Brassinosteroid receptors reveal conserved features of exon-embedded gene regulation",
  "type": "preprint",
  "updated_at": "2026-10-30T12:24:08Z",
  "url": "https://research.draconitic.com/paper/5d4mwds3q35nv",
  "venue": "bioRxiv",
  "versions": []
}