{
  "abstract": "Objective\n\nTo describe the clinical-epidemiological profile of hepatitis C in individuals treated in Pelotas in 2023.Methods\n\nThis was a descriptive study, using data from medical records held at the Injectable Medication Administration and Follow-up Center. Characteristics of the individuals and the disease at the beginning of treatment were used, such as demographic variables, weight, origin of follow-up (public, private), viral load, genotyping, liver fibrosis staging, cirrhosis, human immunodeficiency virus coinfection, and treatment effectiveness. Analyses were stratified by sex, and differences were evaluated by Independent Samples t-test, Wilcoxon test or Fisher's exact test.Results\n\n102 individuals were followed up, i.e. 59 males and 43 females, with mean ages of 52.4 and 57.1 years (p-value 0.037). Human immunodeficiency virus coinfection was 5.9%. 35% of patients assessed underwent genotyping, with type 1 being the most frequent in males and type 3 in females. Adherence among public sector health professionals to the Ministry of Health liver fibrosis staging protocol was higher than among those working in the private sector. One male and six females presented an advanced degree of liver fibrosis (Aspartate Aminotransferase-to-Platelet Ratio Index ≥2) (p-value 0.049) at the start of treatment.Conclusion\n\nMost patients treated for hepatitis C were referred by the public system, with a low degree of fibrosis, although one-third presented some degree of cirrhosis. Disease staging was assessed primarily among public system users. Females were the majority regarding being at an advanced stage of the natural history of the disease. Sustained virological response occurred predominantly among males.",
  "abstract_shown": true,
  "affiliations": [
    "Universidade Católica de Pelotas PelotasRS Brazil Universidade Católica de Pelotas, Pelotas, RS, Brazil.",
    "Universidade Federal de Pelotas PelotasRS Brazil Universidade Federal de Pelotas, Pelotas, RS, Brazil."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Gabriela Breitenbach Santos",
      "orcid": "0000-0002-1955-2708"
    },
    {
      "affs": [
        1
      ],
      "name": "Iná da Silva Dos Santos",
      "orcid": "0000-0003-1258-9249"
    },
    {
      "affs": [
        0
      ],
      "name": "Fernanda Pedrotti Moreira",
      "orcid": "0000-0002-3672-7231"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5dna0kbxbp12p.bib",
  "cited_by": 0,
  "doi": "10.1590/s2237-96222026v35e20250022.en",
  "fulltext_url": "https://europepmc.org/articles/PMC13686298",
  "id": "5dna0kbxbp12p",
  "issns": [
    "1679-4974",
    "2237-9622"
  ],
  "landing_url": "https://europepmc.org/article/MED/42922934",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2721|Hepatitis C virus research"
    ]
  ],
  "openalex": "W7161557481",
  "pdf_url": "https://europepmc.org/articles/PMC13686298?pdf=render",
  "pmcid": "PMC13686298",
  "pmid": "42922934",
  "published": "2026-05-22",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5dna0kbxbp12p.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:02Z",
      "native_id": "MED:42922934",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42922934"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2721|Hepatitis C virus research",
      "subfield": "general"
    }
  ],
  "title": "Profile of people treated for hepatitis C: a descriptive study, Pelotas, Brazil, 2023.",
  "title_text": "Profile of people treated for hepatitis C: a descriptive study, Pelotas, Brazil, 2023.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:02Z",
  "url": "https://research.draconitic.com/paper/5dna0kbxbp12p",
  "venue": "Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil",
  "versions": []
}