{
  "abstract": "Over the past decade, fentanyl and fentanyl analogues have pervaded the illicit drug market and are encountered with growing frequency by law enforcement, HazMat and other first-responder groups. Several studies have addressed the removal of fentanyl from surfaces. However, significantly fewer have focussed efforts on the chemical breakdown of this class of pharmaceuticals. This work presents a new approach to assessing fentanyl decontamination efficacy involving upscaling the reaction between fentanyl (∼15 mg) and the decontaminant, and fractionation of the reaction mixture by medium pressure liquid chromatography (MPLC). This method allowed the identification of surfactant-formulated sodium dichloroisocyanurate as a decontaminant that achieves molecular destruction of fentanyl, rather than simply conversion to the N-oxide of the compound achieved by most recommended degradation methods. The upscaled decontamination assessment approach developed and described herein represents an important reform in decontamination methodology by providing a wider lens through which to assess decontamination efficacy.",
  "abstract_shown": true,
  "affiliations": [
    "School of Chemistry and Molecular Biosciences, The University of Queensland St Lucia QLD 4072 Australia https://www.scmb.uq.edu.au +61 7 3365 3622"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mikaela M. Bazley"
    },
    {
      "affs": [
        0
      ],
      "name": "Avril A. B. Robertson",
      "orcid": "0000-0002-9652-8357"
    },
    {
      "affs": [
        0
      ],
      "name": "Joanne T. Blanchfield",
      "orcid": "0000-0003-1338-7446"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5f514jyv9xeys.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra06255e",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659445/?tool=EBI",
  "id": "5f514jyv9xeys",
  "issns": [
    "2046-2069"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13659445",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Chemistry"
    ],
    [
      "openalex",
      "3005|Forensic Toxicology and Drug Analysis"
    ]
  ],
  "openalex": "W7221661065",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13659445/pdf/?tool=EBI",
  "pmcid": "PMC13659445",
  "pmid": "42871932",
  "published": "2026-10-13",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/5f514jyv9xeys.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:20Z",
      "native_id": "PMC:PMC13659445",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13659445"
    },
    {
      "first_seen": "2026-11-01T12:23:37Z",
      "native_id": "PMC13659445",
      "source": "pmc",
      "url": "https://doi.org/10.1039/d6ra06255e"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:3005|Forensic Toxicology and Drug Analysis",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Assessment and development of decontamination strategies for fentanyl and fentanyl analogues",
  "title_text": "Assessment and development of decontamination strategies for fentanyl and fentanyl analogues",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:20:50Z",
  "url": "https://research.draconitic.com/paper/5f514jyv9xeys",
  "venue": "RSC advances",
  "versions": []
}