{
  "abstract": "MXene is a ubiquitous 2D nanomaterial and is widely used in many applications; however, its catalytic use in organic transformations remains unexplored. Here, we designed and developed palladium nanoparticles stabilised on Nb2CTx MXene (Pd/Nb2CTx) and used the well-characterised nanocomposite as a heterogeneous catalyst for selective aerobic oxidation of benzylic primary and secondary alcohols to corresponding aldehydes and ketones with excellent efficiency. Interestingly, the catalytic application of Pd/Nb2CTx was successfully extended towards a one-pot tandem oxidative condensation strategy for the synthesis of biologically important dihydropyrimidinone/thione derivatives from benzyl alcohols, ethyl acetoacetate, and urea/thiourea. A versatile substrate scope was examined by altering the electronic environment, and good to excellent yields in all cases, ranging 70–98% reveals the vast applicability of the Pd/Nb2CTx nanocatalyst for organic synthesis. The catalyst also demonstrated excellent recyclability, examined up to six consecutive cycles. Furthermore, the recycled heterogeneous catalyst was found to be highly stable, as confirmed by PXRD and FE-SEM analysis. Next, mechanistic investigation deduced the importance of nanostructure as well as the crucial role of the oxygen environment for the catalysis. The present work paves a new way towards exploration of Pd/Nb2CTx MXene nanomaterial as an efficient and recyclable heterogeneous nanocatalyst for organic transformations.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Chemistry, Guru Ghasidas Vishwavidyalaya Koni Bilaspur-495009 Chhattisgarh India",
    "Centre for Nano & Material Sciences, JAIN (Deemed-to-be University) Ramanagaram Karnataka-562112 India",
    "Department of Physics and Astrophysics, University of Delhi Delhi 110007 India"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Muskan Deshmukh"
    },
    {
      "affs": [
        1
      ],
      "name": "Nikhil Dnyaneshwar Shitole"
    },
    {
      "affs": [
        2
      ],
      "name": "Jai Singh"
    },
    {
      "affs": [
        0
      ],
      "name": "Ashish Singh"
    },
    {
      "affs": [
        2
      ],
      "name": "Sevi Murugavel",
      "orcid": "0000-0002-7238-7772"
    },
    {
      "affs": [
        0
      ],
      "name": "Subhash Banerjee",
      "orcid": "0000-0003-3183-6479"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5fyc8m13xbnkp.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra08652g",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13651741/",
  "id": "5fyc8m13xbnkp",
  "issns": [
    "2046-2069"
  ],
  "landing_url": "https://doi.org/10.1039/d6ra08652g",
  "language": "en",
  "licence": "CC-BY-NC-3.0",
  "licence_label": "CC BY-NC 3.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/3.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Chemistry"
    ],
    [
      "openalex",
      "1605|Oxidative Organic Chemistry Reactions"
    ]
  ],
  "openalex": "W7221070449",
  "pdf_url": null,
  "pmcid": "PMC13651741",
  "pmid": "42857665",
  "published": "2026-10-09",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/5fyc8m13xbnkp.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T12:23:34Z",
      "native_id": "PMC13651741",
      "source": "pmc",
      "url": "https://doi.org/10.1039/d6ra08652g"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Oxidative Organic Chemistry Reactions",
      "subfield": "organic"
    }
  ],
  "title": "Nb2CTx Mxene-supported ultrafine palladium nanoparticles for aerobic oxidation of aromatic alcohols and one-pot synthesis of functionalized heterocycles",
  "title_text": "Nb2CTx Mxene-supported ultrafine palladium nanoparticles for aerobic oxidation of aromatic alcohols and one-pot synthesis of functionalized heterocycles",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:20:48Z",
  "url": "https://research.draconitic.com/paper/5fyc8m13xbnkp",
  "venue": "RSC Advances",
  "versions": []
}