{
  "abstract": "Background: Medication adherence after hair transplantation is vital for graft survival and alopecia control, yet adherence to these regimens remains low in routine practice. Nurse-led mHealth shows promise but lacks hair transplant evidence.\n\nMethods: This single-center retrospective cohort study included 200 patients undergoing FUE or FUT at a Chinese hair restoration center (January 2024–June 2025). Those enrolled in a nurse-led mHealth program (n=100) were compared with contemporaneous controls receiving standard care (n=100). Outcomes were extracted from electronic records and the mHealth database. The primary outcome was MARS-5-based medication adherence at 6 months. Secondary outcomes included self-management scores (SMS), DLQI, graft survival, complications, and satisfaction.\n\nResults: At 6 months, the intervention cohort had higher MARS-5 scores than controls (21.55±3.00 vs 13.15±3.78; MD 8.40, 95% CI 7.45–9.35; P<0.001), and higher SMS (77.47±13.33 vs 52.02±14.28; P<0.001), lower DLQI (7.71±4.40 vs 13.98±4.90; P<0.001). High adherence rates were 68% vs 3% (P<0.001). Graft survival was superior (91.99±3.67% vs 87.37±4.87%; P<0.001). mHealth participation was the strongest predictor of adherence (beta=8.612, P<0.001); the association persisted after propensity-score inverse probability weighting (adjusted MD 8.64, 95% CI 7.63–9.65; P<0.001) and in mixed-effects repeated-measures models (cohort-by-time interaction P<0.001).\n\nConclusion: A multicomponent nurse-led digital follow-up program was associated with improved adherence, self-management, quality of life, and graft survival post-hair transplantation. These findings support prospective validation of such programs before routine integration into postoperative protocols.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Nursing, Hangzhou First People’s Hospital, Hangzhou, Zhejiang, 310000, People’s Republic of China",
    "Department of Plastic Surgery, Hangzhou First People’s Hospital, Hangzhou, Zhejiang, 310000, People’s Republic of China"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Lu Xu"
    },
    {
      "affs": [
        1
      ],
      "name": "Haihua Chen"
    },
    {
      "affs": [
        1
      ],
      "name": "Yali Wu"
    },
    {
      "affs": [
        1
      ],
      "name": "Shichang Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Li Ning"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5hdamz9jrqpep.bib",
  "cited_by": 0,
  "doi": "10.2147/ccid.s646672",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13729852/",
  "id": "5hdamz9jrqpep",
  "issns": [
    "1178-7015"
  ],
  "landing_url": "https://doi.org/10.2147/ccid.s646672",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
    ],
    [
      "openalex",
      "3600|Mobile Health and mHealth Applications"
    ]
  ],
  "openalex": "W7224350339",
  "pdf_url": "https://www.dovepress.com/article/download/121576",
  "pmcid": "PMC13729852",
  "pmid": "42979463",
  "published": "2026-10-30",
  "publisher": "Dove Press",
  "ris": "https://research.draconitic.com/paper/5hdamz9jrqpep.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:22:35Z",
      "native_id": "PMC13729852",
      "source": "pmc",
      "url": "https://doi.org/10.2147/ccid.s646672"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:2708|Dermatology and Skin Diseases",
      "subfield": "general"
    }
  ],
  "title": "Association Between a Nurse-Led Mobile Health Intervention and Medication Adherence and Self-Management in Patients After Hair Transplantation: A Retrospective Cohort Study",
  "title_text": "Association Between a Nurse-Led Mobile Health Intervention and Medication Adherence and Self-Management in Patients After Hair Transplantation: A Retrospective Cohort Study",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:22:35Z",
  "url": "https://research.draconitic.com/paper/5hdamz9jrqpep",
  "venue": "Clinical, Cosmetic and Investigational Dermatology",
  "versions": []
}