{
  "abstract": "Introduction: A better 3D visualisation of the lymphatic system could provide more accurate cancer treatment approaches, but this requires contrast agent injections. Since lymphatic vessels are very small, cannulations to administer contrast agent are very difficult to perform manually. As such, a dedicated set up for lymphatic vessel micro cannulations is required. Materials and methods: A micromanipulator rig for full body micro cannulations was constructed. The rig consists of an aluminium frame that can be positioned over a dissection table. It combines the micromanipulator with a sliding gantry plate and a double jointed positioning system to provide as many possible angles of approach as possible. Fluid pressure control devices and a surgical microscope can also be included in the set up. Results: Micro cannulations on a full body could successfully be performed using the micromanipulator rig. After only a short learning curve to explore the movement possibilities/range of the device, the micromanipulator rig quickly outperformed manual micro cannulations. Conclusions: Given the short learning curve and the success rate of the micro cannulations with the micromanipulator rig, we would strongly recommend other microvascular researchers to use the micromanipulator rig for future experiments involving micro cannulations.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Human Structure and Repair, Ghent University, Ghent, Belgium",
    "Cancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium",
    "Evolutionairy Morphology of Vertebrates, Ghent University, Ghent, Belgium",
    "IBiTech-bioMMeda, Ghent University, Ghent, Belgium",
    "Department of Plastic Surgery, Ghent University Hospital, Ghent, Belgium",
    "Breast Clinic, Ghent University Hospital, Ghent, Belgium",
    "Department of Oral Health Sciences, Ghent University, Ghent, Belgium"
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Michael E. J. Stouthandel"
    },
    {
      "affs": [
        1
      ],
      "name": "Danial Forouhar"
    },
    {
      "affs": [
        2
      ],
      "name": "Charlotte Debbaut"
    },
    {
      "affs": [
        3
      ],
      "name": "Jurgen Deviche"
    },
    {
      "affs": [
        4
      ],
      "name": "Liesl De Graeve"
    },
    {
      "affs": [
        5
      ],
      "name": "Bernard Depypere"
    },
    {
      "affs": [
        6
      ],
      "name": "Maarten Meire"
    },
    {
      "name": "Dominique Adriaens"
    },
    {
      "name": "Tom Van Hoof"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5hhveajds7e4a.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pone.0358264",
  "fulltext_url": null,
  "id": "5hhveajds7e4a",
  "issns": [
    "1932-6203"
  ],
  "landing_url": "https://doi.org/10.1371/journal.pone.0358264",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2730|Lymphatic System and Diseases"
    ],
    [
      "plos",
      "/Biology and life sciences/Anatomy/Lymphatic system"
    ],
    [
      "plos",
      "/Biology and life sciences/Anatomy/Musculoskeletal system/Skeleton/Ribs"
    ],
    [
      "plos",
      "/Engineering and technology/Electronics engineering/3D printing"
    ],
    [
      "plos",
      "/Medicine and health sciences/Anatomy/Lymphatic system"
    ],
    [
      "plos",
      "/Medicine and health sciences/Anatomy/Musculoskeletal system/Skeleton/Ribs"
    ],
    [
      "plos",
      "/Medicine and health sciences/Diagnostic medicine/Cancer detection and diagnosis/Lymphatic mapping"
    ],
    [
      "plos",
      "/Medicine and health sciences/Oncology/Cancer detection and diagnosis/Lymphatic mapping"
    ],
    [
      "plos",
      "/Medicine and health sciences/Oncology/Cancer treatment"
    ],
    [
      "plos",
      "/Medicine and health sciences/Surgical and invasive medical procedures/Cannulation"
    ],
    [
      "plos",
      "/Medicine and health sciences/Surgical and invasive medical procedures/Cardiovascular procedures/Vascular surgery"
    ],
    [
      "plos",
      "/Physical sciences/Chemistry/Chemical elements/Aluminum"
    ]
  ],
  "openalex": "W7212284213",
  "pdf_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0358264&type=printable",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-11",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/5hhveajds7e4a.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:56Z",
      "native_id": "10.1371/journal.pone.0358264",
      "source": "plos",
      "url": "https://doi.org/10.1371/journal.pone.0358264"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "plos:oncology",
      "subfield": "oncology"
    },
    {
      "field": "medicine",
      "origin": "plos:anatomy",
      "subfield": "physiology"
    },
    {
      "field": "medicine",
      "origin": "plos:surgical and invasive medical procedures",
      "subfield": "surgery"
    }
  ],
  "title": "Construction of an experimental set up to perform full body micro cannulations of sub-millimetric vessels in an anatomical research setting",
  "title_text": "Construction of an experimental set up to perform full body micro cannulations of sub-millimetric vessels in an anatomical research setting",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:56Z",
  "url": "https://research.draconitic.com/paper/5hhveajds7e4a",
  "venue": "PLOS One",
  "versions": []
}