{
  "abstract": "BackgroundIntramedullary spinal cord metastasis (ISCM) from gastric adenocarcinoma is extremely rare, and treatment is not standardized.Case presentationA 59-year-old man with a 22-month history of gastric adenocarcinoma developed acute quadriplegia during systemic therapy. Contrast-enhanced MRI showed a C3-C4 intramedullary enhancing lesion with extensive edema, and ISCM was suspected on clinical and radiological grounds. Because of the high cervical location and surgical risk, the patient received intensity-modulated radiotherapy (40 Gy in 20 fractions) with sintilimab, nab-paclitaxel, and capecitabine; dexamethasone and mannitol were used for spinal cord edema. Grade 4 neutropenia with febrile neutropenia occurred on radiotherapy day 3, and chemotherapy was stopped. Neurological function improved by radiotherapy day 10. Follow-up cervical MRI showed complete radiographic resolution of the lesion, and limb strength recovered to grade 5. The patient died approximately 6 months after the suspected ISCM diagnosis, about 3 weeks after the last cervical MRI; death was clinically attributed to cachexia from systemic tumor progression, without autopsy.ConclusionThis case showed temporary neurological and radiographic improvement after a multimodal non-surgical approach, but it does not establish the efficacy of an individual treatment component or an overall survival benefit.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "Case Report",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "name": "Yingna Wu"
    },
    {
      "name": "Yu Dai"
    },
    {
      "name": "Tao Fan"
    },
    {
      "name": "Yingjie Song"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5m6axfw897r6h.bib",
  "cited_by": 0,
  "doi": "10.3389/fonc.2026.1996172",
  "fulltext_url": null,
  "id": "5m6axfw897r6h",
  "issns": [
    "2234-943X"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fonc.2026.1996172",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "feed-journal",
      "medicine/oncology"
    ]
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  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-06",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/5m6axfw897r6h.ris",
  "sources": [
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      "first_seen": "2026-11-06T06:20:07Z",
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  "subjects": [
    {
      "field": "medicine",
      "origin": "feed-journal:medicine/oncology",
      "subfield": "oncology"
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  ],
  "title": "Case Report: Multimodal treatment of cervical intramedullary spinal cord metastasis from gastric adenocarcinoma",
  "title_text": "Case Report: Multimodal treatment of cervical intramedullary spinal cord metastasis from gastric adenocarcinoma",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T00:23:06Z",
  "url": "https://research.draconitic.com/paper/5m6axfw897r6h",
  "venue": "Frontiers in Oncology",
  "versions": []
}