{
  "abstract": "目的系统评估1992～2021年中国及全球年龄相关性听力损失（age-related hearing loss， ARHL）的疾病负担变化趋势，分析指标包括患病率（prevalence）和伤残调整生命年（disability-adjusted life years， DALYs）。通过年龄-时期-队列（age-period-cohort， APC）模型，探讨不同年龄、时期和出生队列在ARHL负担变化中的作用，揭示其长期变化特征和潜在影响因素，为制定听力健康干预策略的制订提供循证依据。方法基于2021年全球疾病负担研究（global burden of disease， GBD）数据库，获取1992～2021年中国与全球ARHL的患病率和DALYs数据。采用连接点回归模型（joinpoint regression）评估疾病负担的时间变化趋势，使用年平均百分比变化（average annual percentage change， AAPC）量化趋势幅度。通过APC模型进一步分析年龄、时期和出生队列对ARHL患病率和DALYs的独立影响。结果1992～2021年，中国ARHL的年龄标准化患病率由2万/10万人增至2.2万/10万人，DALYs率由576.35/10万人上升至630.67/10万人。同期，全球患病率由1.7万/10万人增至1.8万/10万人，DALYs率由500.28/10万人升至525.87/10万人。中国患病率与DALYs率的AAPC分别为0.2%与0.3%，全球均为0.2%，提示全球和中国ARHL负担持续增长。性别分布方面，中国男性的ARHL患病人数和患病率高于女性。年龄效应显示，ARHL负担随年龄增长而上升，在65～69岁组达高峰后略降。队列分析提示近出生年代人群的ARHL风险略有下降，可能与健康意识提升和听力保护改善相关。结论1992～2021年，中国及全球ARHL负担总体呈上升趋势，且呈现显著的年龄与性别差异。老年群体尤其是中老年男性是重点关注对象。应加强针对性听力健康管理，推动早筛查、早干预，提升公众听力保护意识。",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "黄芳"
    },
    {
      "name": "廖红明"
    },
    {
      "name": "何本超"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5me3730yaz2v9.bib",
  "cited_by": 0,
  "doi": null,
  "fulltext_url": "http://www.chsr.cn/zh/article/doi/10.3969/j.issn.1672-4933.2026.04.012/",
  "id": "5me3730yaz2v9",
  "issns": [
    "1672-4933"
  ],
  "landing_url": "http://www.chsr.cn/zh/article/doi/10.3969/j.issn.1672-4933.2026.04.012/",
  "language": "zh",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "Limited Liability Company of Chinese Scientific Journal of Hearing and Speech Rehabilitation",
  "ris": "https://research.draconitic.com/paper/5me3730yaz2v9.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:21Z",
      "native_id": "bfe95579f29d4b5e8e9b4cb6f61ad4be",
      "source": "doaj",
      "url": "http://www.chsr.cn/zh/article/doi/10.3969/j.issn.1672-4933.2026.04.012/"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:R",
      "subfield": "general"
    }
  ],
  "title": "年龄相关性听力损失疾病负担的多因素分析",
  "title_text": "年龄相关性听力损失疾病负担的多因素分析",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:21Z",
  "url": "https://research.draconitic.com/paper/5me3730yaz2v9",
  "venue": "Zhongguo tingli yuyan kangfu kexue zazhi",
  "versions": []
}