{
  "abstract": "This study aimed to investigate the association between estimated glucose disposal rate (eGDR) and cataract surgery, and to evaluate the predictive performance of eGDR using machine learning approaches. Using a retrospective cross-sectional design, the present study analyzed data sourced from the 2001–2008 National Health and Nutrition Examination Survey, which encompassed a total of 41,658 participants. Propensity score matching was used to balance the following covariates: age, gender, race, and the poverty-to-income ratio. The analytical methods used in this study included logistic regression and restricted cubic splines to examine nonlinearity relationships. Additionally, eXtreme Gradient Boosting-SHapley Additive exPlanations (SHAP) modeling was used to evaluate the importance of the predictors. An inverse dose-dependent relationship was observed: for each unit increase in eGDR, the odds of undergoing cataract surgery decreased (odds ratio = 0.914, 95% confidence interval: 0.875–0.954, P < .001). The highest eGDR quartile showed the strongest protective effect (Q4 vs Q1: odds ratio = 0.69, P = .0087). Restricted cubic spline analysis revealed a threshold of eGDR = 5.693 mg/kg/minutes. Above this threshold, the cataract surgery rate decreased linearly. Stratified analyses revealed a significant protective effect in individuals aged ≥60 years (P = .001), and observed stronger inverse associations in high-income subgroups (P = .02). eXtreme Gradient Boosting-SHAP modeling identified eGDR as a pivotal predictor (mean SHAP = 0.008), surpassing the performance of the traditional clinical indices. Elevated eGDR levels are associated with a lower rate of cataract surgery, which is modulated by age and socioeconomic status.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Ophthalmology, Xinhui District People’s Hospital, Jiangmen, China",
    "Department of Clinical Laboratory, Xinhui District People’s Hospital, Jiangmen, China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Guoan Liu",
      "orcid": "0009-0007-7922-6107"
    },
    {
      "affs": [
        0
      ],
      "name": "Yanman Zhong"
    },
    {
      "affs": [
        0
      ],
      "name": "Ruimei Qin"
    },
    {
      "affs": [
        0
      ],
      "name": "Jiaying Wang"
    },
    {
      "affs": [
        1
      ],
      "name": "Jinling Xie",
      "orcid": "0000-0003-1888-6009"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5na6pgj5gj4ap.bib",
  "cited_by": 0,
  "doi": "10.1097/md.0000000000051292",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727194/?tool=EBI",
  "id": "5na6pgj5gj4ap",
  "issns": [
    "0304-5412",
    "1536-5964",
    "0025-7974"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13727194",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "4700"
    ],
    [
      "heading",
      "Observational Study"
    ],
    [
      "heading",
      "Research Article"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13727194/pdf/?tool=EBI",
  "pmcid": "PMC13727194",
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Wolters Kluwer Health",
  "ris": "https://research.draconitic.com/paper/5na6pgj5gj4ap.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T15:20:51Z",
      "native_id": "PMC:PMC13727194",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13727194"
    },
    {
      "first_seen": "2026-11-05T12:23:20Z",
      "native_id": "PMC13727194",
      "source": "pmc",
      "url": "https://doi.org/10.1097/md.0000000000051292"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:F27",
      "subfield": "general"
    }
  ],
  "title": "Association between estimated glucose disposal rate and history of cataract surgery : A population-based cross-sectional study from NHANES",
  "title_text": "Association between estimated glucose disposal rate and history of cataract surgery : A population-based cross-sectional study from NHANES",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:22:55Z",
  "url": "https://research.draconitic.com/paper/5na6pgj5gj4ap",
  "venue": "Medicine",
  "versions": []
}