{
  "abstract": "Intramuscular myxoma is a rare benign mesenchymal tumor of skeletal muscle that usually presents as a slowly enlarging, painless mass. We report a giant intramuscular myxoma of the distal gluteus maximus in a 34-year-old woman. The lesion became clinically apparent during the third trimester of her first pregnancy and enlarged rapidly over approximately 6 months. Three months after cesarean delivery, she presented with severe sitting intolerance, difficulty breastfeeding while seated, and burning pain radiating along the sciatic nerve distribution. Magnetic resonance imaging demonstrated an approximately 154 × 155 × 156 mm well-circumscribed intramuscular mass adjacent to the ischium and compressing the sciatic nerve, without osseous destruction; however, its rapid growth and imaging features raised concern for a malignant myxoid soft-tissue neoplasm. A preoperative core needle biopsy showed fibrous and myxoid tissue, with no atypia or malignant cells identified in the sampled material. Complete en bloc excision was performed. Histopathologic and immunohistochemical evaluation confirmed intramuscular myxoma, and the closest surgical margin was 1 cm. The postoperative course was uneventful; symptoms resolved, she was able to continue breastfeeding, and no clinically evident local recurrence was observed during 24 months of clinical follow-up. This case highlights that a histologically benign intramuscular myxoma may exhibit rapid growth during late pregnancy, reach giant size, and mimic a malignant process, thereby creating substantial preoperative diagnostic uncertainty.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Orthopaedics and Traumatology, Ufuk University Medical Faculty, Ankara, Turkey."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Cem Güneri",
      "orcid": "0000-0002-6298-9876"
    },
    {
      "affs": [
        0
      ],
      "name": "Yasin Köker",
      "orcid": "0000-0002-8392-1846"
    },
    {
      "affs": [
        0
      ],
      "name": "İsmet Teoman Benli",
      "orcid": "0000-0002-1878-0653"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5nvvvw2kbzftn.bib",
  "cited_by": 0,
  "doi": "10.13107/jocr.2026.v16.i11.8420",
  "fulltext_url": "https://europepmc.org/articles/PMC13740904",
  "id": "5nvvvw2kbzftn",
  "issns": [
    "2250-0685",
    "2321-3817"
  ],
  "landing_url": "https://europepmc.org/article/MED/42997035",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2734|Soft tissue tumors and treatment"
    ]
  ],
  "openalex": "W7225570835",
  "pdf_url": "https://europepmc.org/articles/PMC13740904?pdf=render",
  "pmcid": "PMC13740904",
  "pmid": "42997035",
  "published": "2026-11-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5nvvvw2kbzftn.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T15:20:34Z",
      "native_id": "MED:42997035",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42997035"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2734|Soft tissue tumors and treatment",
      "subfield": "general"
    }
  ],
  "title": "Rapidly Enlarging Giant Intramuscular Myxoma of the Distal Gluteus Maximus during Late Pregnancy.",
  "title_text": "Rapidly Enlarging Giant Intramuscular Myxoma of the Distal Gluteus Maximus during Late Pregnancy.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T15:20:34Z",
  "url": "https://research.draconitic.com/paper/5nvvvw2kbzftn",
  "venue": "Journal of orthopaedic case reports",
  "versions": []
}