{
  "abstract": "Immune checkpoint inhibitors (ICIs) are widely used for advanced lung cancer; however, isolated ileitis and subsequent perforation are rare, particularly when complicated by cytomegalovirus (CMV) infection.A woman in her 50s with stage IV lung adenocarcinoma developed ICI-associated enteritis after atezolizumab-based therapy, which partially improved with corticosteroids and infliximab, but she later experienced ileal perforation following second-line chemotherapy. A histopathological examination revealed ICI-induced enteritis with cytomegalovirus (CMV) inclusions. Despite antiviral therapy with ganciclovir, the patient died. We present the first report of pathologically confirmed ICI-induced ileitis complicated by CMV enteritis in resected small bowel tissue.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "Yuka Yamada"
    },
    {
      "name": "Norio Kodaka"
    },
    {
      "name": "Saeko Shinozawa"
    },
    {
      "name": "Yuki Yokouchi"
    },
    {
      "name": "Hiroto Matsuse"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5pcdkrc089c5b.bib",
  "cited_by": 1,
  "doi": "10.2169/internalmedicine.7426-26",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7426-26/_article",
  "id": "5pcdkrc089c5b",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7426-26/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2730|Cancer Immunotherapy and Biomarkers"
    ]
  ],
  "openalex": "W7204119808",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7426-26/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-25",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5pcdkrc089c5b.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.7426-26",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7426-26/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Cancer Immunotherapy and Biomarkers",
      "subfield": "oncology"
    }
  ],
  "title": "Concurrent Immune-related Enteritis and Cytomegalovirus Enteritis during Immune Checkpoint Inhibitor Therapy",
  "title_text": "Concurrent Immune-related Enteritis and Cytomegalovirus Enteritis during Immune Checkpoint Inhibitor Therapy",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/5pcdkrc089c5b",
  "venue": "Internal Medicine",
  "versions": []
}