{
  "abstract": "Chronic low-grade systemic inflammation contributes to chronic diseases. The dietary inflammatory index (DII) is a validated tool for quantifying diet-related inflammation; however, its assessment methods are limited. This study developed a simplified DII (S-DII) based on a 25-item food frequency questionnaire (FFQ25). To validate the S-DII, we evaluated 269 community-dwelling older adults in China. Dietary intake data were measured using the FFQ25 and 24-h dietary recall (24HR). Fasting blood samples were collected to quantify inflammatory markers, including C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin (IL)-4, IL-6, IL-10, and IL-1β. To examine applicability, an additional 983 older adults were recruited. The S-DII demonstrated moderate concordance with the DII calculated from 24HR data (r = 0.640, intraclass correlation coefficient = 0.615, p < 0.05) and was supported by Bland–Altman analysis. CRP and IL-1β were positively associated with the S-DII after controlling covariates, whereas no significant associations were found for S-DII with TNF-α, IL-4, IL-6, or IL-10. In the larger cohort (n = 983), intake of cereals, tubers, red meat, poultry, soybeans, nuts, vegetables, and fruits was significantly higher among adults with the lowest S-DII values, while dairy and egg consumption showed an inverse trend (p < 0.05). Higher S-DII scores were significantly associated with higher odds of hypertension and coronary heart disease after covariate adjustment. The S-DII demonstrated strong validity and feasibility as an assessment tool for diet-related inflammation. These preliminary findings indicated that the S-DII could serve as a time-efficient screening tool for dietary inflammatory potential, assisting targeted nutritional prevention of chronic diseases among community-dwelling older adults with similar regional characteristics.",
  "abstract_shown": true,
  "affiliations": [
    "School of Nursing, Ningxia Medical University",
    "General Hospital of Ningxia Medical University",
    "Wuzhong People’s Hospital"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Ting Jiang"
    },
    {
      "affs": [
        1
      ],
      "name": "Xiongxiong Lv"
    },
    {
      "affs": [
        1
      ],
      "name": "Weijuan Kong"
    },
    {
      "affs": [
        2
      ],
      "name": "Haiyan Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Jing Shi"
    },
    {
      "affs": [
        0
      ],
      "name": "Lingna Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Yanhua Ning"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5pexqzqy91jww.bib",
  "cited_by": 0,
  "doi": "10.1038/s41598-026-62594-0",
  "fulltext_url": "https://doi.org/10.1038/s41598-026-62594-0",
  "id": "5pexqzqy91jww",
  "issns": [
    "2045-2322"
  ],
  "landing_url": "https://doi.org/10.1038/s41598-026-62594-0",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "Q"
    ],
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "2739|Nutritional Studies and Diet"
    ]
  ],
  "openalex": "W7169591282",
  "pdf_url": "https://www.nature.com/articles/s41598-026-62594-0_reference.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "Nature Portfolio",
  "ris": "https://research.draconitic.com/paper/5pexqzqy91jww.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:58Z",
      "native_id": "b40f41b508cc4f72a0bd5a63d415139a",
      "source": "doaj",
      "url": "https://doi.org/10.1038/s41598-026-62594-0"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2739|Nutritional Studies and Diet",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Validity and feasibility of the simplified dietary inflammatory index in Chinese older adults",
  "title_text": "Validity and feasibility of the simplified dietary inflammatory index in Chinese older adults",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:58Z",
  "url": "https://research.draconitic.com/paper/5pexqzqy91jww",
  "venue": "Scientific Reports",
  "versions": []
}